Confocal Raman microscopy is a powerful tool for analyzing the chemical composition of samples. With the alpha300 apyron WITec takes 3D Raman imaging automation to the next level. It combines ease-of-use and ultimate capability by automating hardware control and offering pre-configured measurement routines. This streamlines the experimental workflow and yields reproducible results with unrivaled speed, sensitivity and resolution. The alpha300 apyron can self-align and self-calibrate, which substantially reduces the researcher’s experimental workload by requiring less user input, enhancing reproducibility and eliminating potential sources of error.