BÜCHI Labortechnik AG

Model B-395 Pro - Encapsulator for Sterile Microbeads and Microcapsules

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A quality product for the sterile encapsulation of cells, biological and active ingredients for laboratory-scale research and development work. The highly advanced technology enables particle production for numerous biotechnology and medical processes and other fields that require sterile conditions.

Aseptic

  • Sterile encapsulation of cells, microorganisms and active ingredients
  • Aseptic introduction and removal of fluids and products to and from the reaction vessel
  • Possibility of integration in a GMP-compliant production process

Reliable

  • Efficient, reproducible encapsulation process under low-impact process conditions
  • Exceptionally tight particle size distribution
  • High encapsulation efficiency and yield

User-friendly

  • Intuitive to operate and easy to maintain
  • Quick and easy process optimization thanks to visualization of droplet formation
  • The BUCHI application database and BUCHI application support help you get the most out of working with the Encapsulator B-395 Pro

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Syringe Pump

Easily calibrated syringe pump for low-loss feed of small sample quantities using sterile syringes of various volumes.

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Material Certificates

The reaction vessel for the Encapsulator B-395 Pro is available with material certificates for GMP documentation.

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Concentric Nozzle System

Concentric nozzle system for creating core-shell capsules (dia. 200 – 2000 µm).

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Air Dripping Nozzle

Nozzle system with airstream dispersal and minimized dead space, tailor-made for low-impact encapsulation of cell agglomerates.

  • Dimensions (W x D x H): 320 x 480 x 380 mm
  • Weight: 11 kg
  • Power consumption: max. 150 W
  • Connection voltage: 100-240 VAC
  • Frequency: 50/60 Hz
  • Vibration frequency: 40 to 6000 Hz
  • Electrode tension: 250 to 2500 V
  • Nozzle diameter of single nozzles: 0.08, 0.12, 0.15, 0.2, 0.3, 0.45, 0.75, 1.0 mm

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Spray Drying & Encapsulation Pharmaceuticals

Active pharmaceutical ingredients, drug delivery, vaccines, inhalable drugs, taste masking.

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Spray Drying & Encapsulation Food

Encapsulation of additives, controlled release, nutraceuticals, functional foods, flavors, vitamins, proteins, probiotic bacteria, juice concentrate, milk powder.

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Spray Drying & Encapsulation Feed

Encapsulation of additives, flavors, vitamins, proteins, probiotic bacteria, controlled release.

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Spray Drying & Encapsulation Others

Cell, bacteria and protein encapsulation, cell transplantation, biotransformation, cosmetics, fragrances, environmental applications.

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Spray Drying & Encapsulation Academia

For a wide range of applications in academic education: Full range of spray drying applications.

Set of 8 single nozzles

Set of 8 single nozzles with high precision opening of 0.08, 0.12, 0.15, 0.20, 0.30, 0.45, 0.75 and 1.00 mm, made of stainless steel including nozzle rack.

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Set of 8 single nozzles

Set of 8 single nozzles with high precision opening of 0.08, 0.12, 0.15, 0.20, 0.30, 0.45, 0.75 and 1.00 mm, made of stainless steel including nozzle rack.

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Concentric nozzle set

Set of 7 external nozzles with high precision opening of 0.2, 0.3, 0.4, 0.5, 0.6, 0.7 and 0.9 mm made of stainless steel incl. 1000 mL pressure bottle.

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Flow vibration nozzle set

Nozzle set for high viscose solutions and smaller beads. Pulsation chamber core vibrated plus a set of 7 external nozzles with high precision opening of 0.2, 0.3, 0.4, 0.5, 0.6, 0.7 and 0.9 mm made of stainless steel, incl. air flow controller.

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Air dripping nozzle set

Nozzle set for agglomerates and islet cells. Chamber, core nozzle 0.4mm, shell nozzle 1.5mm, air flow controller, incl. 2 short glass cylinders.

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Reaction vessel for sterile apllications

Completely autoclavable reaction vessel made of glass and stainless steel for the sterile production and collection of microcapsules, 2 litre working volume; incl. bead producing unit and set of 8 single nozzles.

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