- Model Quaternary - HPLC/UHPLC System


An economical option for gradient analysis is a quaternary HPLC system with a single pump and valve to mix up to four solvents. The Nexera quaternary system operates at analytical to semi-prep flows (max. 10 mL/min) and throughout the HPLC and UHPLC pressure range, up to 19,000 psi, with no compromises in gradient performance. The quaternary valve also functions as a solvent selector which adds different solvent ratios for pH or mobile phase modifier adjustment. When 2 pumps each with a quaternary valve are configured, the resulting high pressure binary gradient lets the analyst select from any of the 4 solvents in each pump, creating an automatic method development system with 16 mobile phase pairs. The flexibility of the Nexera quaternary system as a standalone gradient pump, solvent blender, or solvent selector for method development makes it an ideal choice to support the varying needs of a fast-paced R&D environment.

  • Capable of 4-solvent gradient analysis at UHPLC system pressures up to 130 MPa
  • Seamless method transfer from conventional HPLC to UHPLC
  • Highly accurate solvent delivery ensures reliable analysis
  • Applicable for a wide range of applications, including method development

  • Compatible with maximum 4-solvent gradient at UHPLC pressures up to 130 MPa, the world’s highest, the Nexera
  • Quaternary system can be utilized for a wide range of applications, from conventional HPLC to UHPLC. Its design allows
  • users to pre-set 4 solvents, enabling the use of multiple combinations of solvents in the method development process. This makes the method development process more efficient while reducing the labor associated with preparing solvents.

Analysis of 8 compounds of Non-Steroidal Anti-Inflammatory Drugs

Analysis of 8 compounds of Non-Steroidal Anti-Inflammatory Drugs

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