SCIEX - CESI 8000 Plus
From Front-End HPLC MS - Ultra-Low Flow
Product Details
Get the most from that precious material and hunt down the hidden information you couldn’t see before:
- Intact mAb charge variants with online MS detection
- Proteoforms & peptide PTMs such as those with multiple phosphorylation sites
- Challenging charged & polar metabolites/degradation products such as anionic and/or hydrophilic analytes
- Isobaric metabolites and glycans not resolved by traditional techniques
- Protein conformation and quantitation
The integration of Capillary Electrophoresis with Electrospray Ionization into a single dynamic process within the same device brings new capabilities to researchers.
The CESI 8000 Plus high-performance system delivers fast, efficient and unique separation selectivity with enhanced sensitivity, while simultaneously expanding coverage.
Learn why capillary electrophoresis - mass spectrometry (CE-MS) is an attractive microscale analytical technique for addressing biological questions inherently dealing with low amounts of material.
Simplify the analysis of isobaric compounds inadequately resolved with current methods.
Study the molecular interactions and structure of your proteins and peptides under native conditions.
Expanded coverage allows you to see more than ever before.
Reveal hydrophilic charged and polar compounds and increase sensitivity in your metabolome and glycome analysis, not possible with LC methods.
Confidently quantify and characterize proteoform and peptide PTMs, such as those with multiple phosphorylation and glycosylation sites.
Resolve isomers – unseeable with traditional LC-MS methods.
More Dynamic, Efficient Processes
CESI-MS allows for a more robust system with ultra-low-flow < 10 nL/min, into the mass spectrometer resulting an overall increase in ionization efficiency.
Samples are often limited in quantity. CESI-MS has nL sample consumption, leaving most of the material available for analysis by orthogonal techniques.
Use the same method and reagents for multi-level characterization of protein therapeutics. Switch between pos and neg ion modes without changing setup.
Frustration Free
Open tube technology eliminates frustrations common with nanoscale techniques. No more minimizing dead volumes, or dealing with carryover and clogs.
Key Features
- Zero Dead Volume Single continuous separation capillary is contained within the OptiMS cartridge
- Multi-Detection Capability In stand-alone CE mode, UV/VIS, PDA, or LIF detection can be selected
- Multiple Injections from Precious Samples Sample analysis from as little as 5 μL
- Dimensions 29.2 in (74.2 cm) H x 25 in (63.5 cm) W x 28.4 in (72.1 cm) D
- Portable Lab Bench 36 in x 30 in (91.4 cm x 76.2 cm)
- Height adjusts 27 in to 44 in (69 - 112 cm)
- Weight (uncrated) 188 lbs (85.3 kg)
- Electrical Requirements Voltage: 100 - 240 V; 50/60 Hz
- Sample Trays 2 x 48 CESI vials / 0.3 mL microvials
- Buffer Tray 2 x 36 CESI vials
- Pressure Delivery Range -5 to +100 PSI
- Required Sample Volume 5 μl when using NanoVias
Customer reviews
No reviews were found for SCIEX - CESI 8000 Plus. Be the first to review!