GE Analytical Instruments

- Model 500 RL - On-Line TOC Analyzer



The Sievers 500 RL On-Line Total Organic Carbon (TOO Analyzer provides continuous monitoring of organics in ultrapure water for pharmaceutical and power applications. The reagentless 500 RL provides the superior analytical accuracy and performance found in all Sievers TOC Analyzers, and offers a range of options meet specific customer needs.

Science-based Design
The Sievers membrane conductometric design eliminates false positive and false negative readings to which other technologies are susceptible. Additionally, the Sievers' technology ensures accurate recovery of all classes of organic compounds commonly found in UPW waters. In a process capability study comparing on-line TOC analyzers,1 the Sievers 500 RL was the only analyzer that demonstrated a meaningful statistical process capability, making it the only on-line TOC analyzer providing confidence that UPW processes are fully protected.

Ease of Use
The 500 RL is exceptionally easy to install, operate, and maintain. It includes a large color touch-screen display, intuitive menu interface, on-screen consumables status indicators with maintenance prompts, and advanced auto-zero features for improved low-level performance.

The Sievers 500 RL is designed to deliver science-based risk management capability to the production floor. It provides reagentless on-line TOC analysis for compliance with   US   Pharmacopeia  (USP)  <643>,

European Pharmacopeia (£P) 2.2.44 Total Organic Carbon, Indian Pharmacopeia (IP) 2.4.30, Chinese Pharmacopeia (CP) Appendix VIII R, and the Japanese Pharmacopeia 16 (JP16) 2.59 monographs for Purified Water and Water for Injection.

The 500 RL base model can be configured or upgraded with a variety of hardware and software options at any time. Two options are available for introducing calibration and system suitability grab samples: the standard single-port iOS* (Integrated On-line Sampling System) and the automated four-port Super iOS.

In addition to the Super iOS, options specifically for pharmaceutical customers include USP Chapter <645> conductivity measurement, automated USP system suitability, linearity functionality, and Sievers DataGuard* for facilitating 21 CFR Part 11 compliance. The optional DataShare* 500 enables all customers to view, share and create reports from the 500 RL's encrypted data USB output.

GE Analytical Instruments provides ongoing technical support, as well as on-site installation, maintenance, calibration, and training services that together assure optimal performance from Sievers instruments. For more information, visit

Total Organic Carbon

  • Linear Range : 0.03 to 2,500 ppb as C
  • Accuracy : ± 5% of measurement
  • Precision : < 1% RSD or 0.03 ppb as C, whichever is greater
  • Analysis Modes : On-Line, On-Line Averaged, On-Line Timed, Analysis Time Continuous mode: 6 minutes Average and timed modes: 0.5, 1, 4, 8, or 24 hours
  • Ozone Compatibility3 : Maximum 200 ppb as O3
  • External Flow Rate : Minimum 50 mL/min
  • Sample Temperature : 1° C to 95° C (34° F to 203° F)
  • Sample Pressure : Up to 100 psig
  • Interferences : Insensitive to organic heteroatoms
  • Calibration Stability : Typically stable for 12 months
  • Display Readout : 3 significant digits


  • Raw Conductivity Range4 : 0.01 to 35 μS/cm
  • Conductivity Accuracy3,4 :  ± 0.005 μS/cm or ± 1%, whichever is greater
  • Conductivity Precision : < 0.25% RSD
  • Maximum Sample Conductivity :  25 μS/cm at neutral pH

Instrument :

  • Power : 100-240 ±10% VAC, 50 Wt 50/60 Hz
  • Normal Operating Environment : Intended for indoor use only
  • Ambient Temperature : 10° C to 40° C 150° F to 104° F)
  • Maximum Relative Humidity : Up to 95%, noncondensing
  • Maximum Altitude : 2.300 m {7f546 ft)
  • Inputs : One isolated binary input
  • Outputs : Three isolated 4-20mA outputs, one Serial (RS-232), one USB port.3 one parallel printer port, tour alarm outputs, and one Ethernet port Category II (protects against transients present in Category II power! Installation/Overvoltage
  • Safety Certifications : E*L. CE
  • Pollution Degree : 2 (normally only non-conductive pollution)
  • Display : Backlit Quarter-VGA touchscreen display
  • Dimensions : H: 41.9 cm (16.5 in); W: 48.3 cm 119 in); D: 27.4 cm (10.8 in)
  • Weight : 16.9 kg (37.2 lb)
  • IP Rating : Environmental Enclosure: IP 45

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