Waters Corporation

Waters Atmospheric Pressure Gas Chromatography (APGC)



Waters Atmospheric Pressure Gas Chromatography (APGC) adds GC capability to today’s advanced MS technologies.

This provides GC users with:

  • High performance, ease of use allowing quick reaction to meet demands and increase throughput
  • Access to ultra-trace quantification
  • Comprehensive qualitative MS & MS/MS
  • High-resolution ion-mobility separations.
GC capabilities for today’s advanced MS technologies

APGC is an ionisation source for Xevo® and SYNAPT® mass spectrometers. The ionisation is ‘soft‘ meaning that less fragmentation is observed for many compounds when compared with techniques such as EI. Reduced fragmentation can give higher sensitivity and specificity, therefore simplifying pre-cursor ion selection in MS/MS analyses.

Waters® Universal source architecture and Engineered SimplicityTM means that changeover from UPLC® to GC is quick and simple. Since APGC is not a vacuum technique equilibration time between techniques is kept to a minimum. This means that analysis can be tailored to business demands, maximizing up-time and instrument utilization.

Waters enhanced, unique MS technologies such as RADARTM, MSE & HDMSTM are now available to GC separations. Unlock the secrets of your sample and make sure you have the widest possible coverage from your analyses.

Xevo TQ-S with APGC - Ultra Trace Quantification

Xevo TQ-S APGC equipped with unique StepWaveTM technology, enabling detection limits at ultra-trace levels. This allows compliance with regulatory limits and the ability to inject less sample matrix, reducing effects of contamination on the GC-MS system and therefore increasing uptime. The unique source design offers high levels of matrix tolerance and gives excellent injection to injection repeatability. StepWave ion transfer optics and detection technology allow accurate and precise quantification over the widest dynamic range.

Xevo G2-S QTof with APGC – Identify, quantify and confirm the broadest range of compounds with GC

Many analyses cross the boundary between LC & GC. The Waters Xevo G2-S QTof enables complete screening of samples using both ACQUITY UPLC® and GC separations. MSE allows the scientist to get exact mass precursor and fragment ion spectra from every detectable component in the sample, simplifying the identification of components.

Innovative geometry and ion detection system combine in the QuanTofTM to enhance sensitivity and provide outstanding chromatographic compatible mass resolution, matrix tolerant in spectrum dynamic range, quantitative performance and mass accuracy.

Xevo G2-S QTof is designed for scientists who need to indentify, quantify and confirm the broadest range of compounds in the most complex and challenging samples.

SYNAPT G2-Si with APGC – Research grade, high-resolution, ion mobility separations for GC

APGC gives access to high-end research grade, high-resolution, ion mobility separations previously unavailable to GC users and provides a range of unique experimental capabilities to make new discoveries possible that are beyond any other analytical platform.

This combination of mass accuracy, resolution and ion mobility gives unsurpassed levels of selectivity providing sample information never before obtainable.

Superior separation is facilitated with high-efficiency T-WaveTM Ion Mobility Separation which adds an extra dimension of resolution to your analysis. This combination of leading edge technology makes a wider range of experimental options possible than ever before, enabling you to get maximum information from your sample.

SYNAPT delivers a third dimension to your analysis, proven to transform your analytical perspective whatever the application.

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