ANTEC GmbH Analysen- und Prozesstechnik products

Gel Permeation Chromatography (GPC)

ANTEC - Gel Permeation Chromatography (GPC)

Gel Permeation Chromatography (GPC) is an effective separation technique used, among other things, for sample preparation and extract purification within various analytical processes. The GPC is especially valuable for modular analysis of pesticide residues from food matrices as per ASU L00.0034, showing superiority in terms of extract purification and reducing residues compared to other methods like ASU L00.00113 and ASU L00.00115. It helps achieve higher total extract volumes and often lower determination limits for numerous analytes using identical detection principles. This process significantly reduces the load on downstream chromatographic systems (GC-MS/MS and LC-MS/MS), resulting in minimized maintenance and thus indirect savings in time and costs. The traditional GPC glass column has a gel bed made of porous, crosslinked polystyrene beads, through which the solvent system (often cyclohexane: ethyl acetate) flows at a rate of 5 ml per minute. Low molecular weight substances are slowed down within the gel bed, whereas high molecular weight substances migrate around the beads and reach the top of the column faster, where they are diverted to waste via an automatic valve. The slower-moving substances are directed either to the AccuVap module for simultaneous evaporation or collected in round-bottom flasks. The main advantage of the GPC method lies in the cleanliness of the eluates and the fact that virtually all active ingredients are contained in a fraction of roughly 100 to 250 ml, allowing for the collection through a single sample preparation step. The modular PrepLinc platform offers fully automated sample preparation and extract clean-up, and it is suitable for various sample types including food, water, feed, environmental, fuel, pharmaceutical, and human samples. This platform significantly streamlines and automates laborious and extensive steps of sample cleaning processes.

ANTEC - Gel-Permeation Chromatography System for High Lipid Content Samples

ANTEC GmbH introduces the PrepLinc 2™ 2D Gel-Permeation Chromatography (GPC) system, specifically designed for the separation and purification of large molecules, especially fats and oils. Traditional GPC systems often struggle with high lipid content samples, requiring multiple runs to achieve the desired level of purification. The PrepLinc 2D GPC system allows for the injection of up to five grams of lipid matrix in a single run, significantly reducing processing time and solvent usage while increasing sample throughput. This system employs a two-column setup, enabling the processing of a larger sample volume and achieving optimal separation in a single injection. This innovation addresses the limitations of conventional GPC columns, which typically handle only one gram of matrix per run. The 2D GPC system is easily upgradable for existing PrepLinc systems and is optionally available for new installations. It has proven effective in applications such as dioxin analysis, where multiple GPC runs are standard practice, thus saving time and resources. For detailed application notes and technical support, ANTEC GmbH offers comprehensive service and consultation.

TOC Analyzers

ANTEC - TOC Analyser with Catalytic Oxidation

The TOC Analyser Torch from ANTEC GmbH employs catalytic oxidation for the breakdown of organic carbon. It features a wide measurement range from 50 ppbC to 30,000 ppmC, effectively handling salt- and particle-laden samples. The system utilizes a catalytic oxidation method combined with NDIR detection, concentrating and analyzing the entire sample within the NDIR detector. The Torch offers automated calibration and dilution functions via an integrated PC, streamlining operation and ensuring accurate measurements. Maintenance is simplified due to the well-organized arrangement of components, making all parts easily accessible. The analyser meets 21 CFR Part 11 requirements, making it suitable for use in the pharmaceutical industry requiring FDA clearance. It supports comprehensive validation documentation for IQ/OQ/PQ processes and cleaning validation. The static pressure concentration (SPC) NDIR detector accumulates carrier gas and CO2 molecules, measuring the total TOC content in a single operation, beneficial for low-end measurement accuracy. The automated sample feeder can handle various sample racks, ensuring efficient sample preparation and analysis. The system is compatible with official methods for measuring TOC in various water types, including drinking water, surface water, groundwater, and wastewater.

Purge & Trap

ANTEC - Purge and Trap Concentrator

The LUMIN Purge & Trap sample preparation system from Teledyne Tekmar effectively removes volatile organic compounds (VOCs) from aqueous samples using helium or nitrogen. These VOCs are then transferred to a sorption trap, released under heat, and analyzed via gas chromatography. The LUMIN system is a culmination of seven previous generations of VOC equipment, building on the proven efficacy of the Purge and Trap technique. The method involves introducing a purge gas through a sample matrix to collect VOCs in an analytical trap. The LUMIN features key components essential for accurate Purge & Trap analysis, including an electronic mass flow controller (MFC), superior trap technology, and an inert sample pathway. The U-shaped trap is designed to adsorb VOCs while minimizing unwanted water accumulation. The system's ultra-fast trap heater ensures rapid desorption of VOCs, while a specialized cooling mechanism minimizes downtime, boosting throughput. The inert sample pathway reduces carryover for reliable calibration. The LUMIN also integrates advanced features like moisture control, automatic leak checks, foam detection, and software-driven diagnostic and self-test capabilities.