Ascendia Pharmaceutical Solutions products

LipidSol is a proprietary lipid nanoparticle technology developed by Ascendia Pharmaceutical Solutions. Composed of lipid-based assemblies, LipidSol works to encapsulate small and large molecules as well as biologics in nanoparticle structures. 

AmorSol is a technology for the production of amorphous solid dispersions. Formulation of a drug substance in amorphous form greatly improves its solubility and dissolution kinetics, and has become a standard formulation technique in the pharmaceutical industry for reaching bioavailability goals for poorly water soluble drugs. Amorphous drug substance forms are meta-stable, and can be stabilized by using various polymers to restrict or delay recrystallization of the drug.  Solid dispersions are used to increase the dissolution rate, a limiting factor for the absorption of many compounds in development today. A solid dispersion is a dispersion of the compound in a solid, inert matrix carrier, generally a poorly water soluble drug in a hydrophilic carrier (e.g., a polymer).