Ascendia Pharmaceuticals products

AmorSol is a technology for the production of amorphous solid dispersions. Formulation of a drug substance in amorphous form greatly improves its solubility and dissolution kinetics, and has become a standard formulation technique in the pharmaceutical industry for reaching bioavailability goals for poorly water soluble drugs. Amorphous drug substance forms are meta-stable, and can be stabilized by using various polymers to restrict or delay recrystallization of the drug.

NanoSol is a technology for the production of nano-sized drug particles. Formulation of a drug substance in nano-particle form significantly increases the surface area available for dissolution.  A ten-to-twenty-fold increase in surface area can result from reducing particle size from a micronized drug substance to a nanonized drug substance.