Bilix Co., Ltd.
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Bilix Co., Ltd. products

BRIXELLE Platform

BRIXELLE-ONCO - Bilirubin Nanoparticle Molecule

A bilirubin nanoparticle is made of poorly soluble bilirubin core and hydrophilic PEG shell. The nature of bilirubin allows anti-cancer drugs to be easily encapsulated in the nanoparticle via hydrophobic interaction. Although there are many anti-cancer drugs available, patients are still suffering from side effects due to drug toxicity. Our BRIXELLE-ONCO technology focuses on alleviating patients’ suffering by minimizing side effects by utilizing bilirubin nanoparticles as non-toxic drug carrier. Our bilirubin nanoparticle is synthesized by conjugating well validated PEG to the bilirubin molecule. As bilirubin naturally exists in the body and safety of PEG is already well known, the bilirubin nanoparticle itself possesses no toxicity.