BioAssay Systems products

Application; For quantitative determination of acetic acid or acetate and evaluation of drug effects on acetate metabolism.

β-N-Acetylglucosaminidase (NAG) is a lysosomal enzyme involved in a variety of biological processes such as the degradation of glycoproteins and glycolipids, cell proliferation, and signal transduction. NAG is found in many tissues in the body, but due to its high molecular weight, it can not be filtered through the glomerular membrane. For this reason, in the presence of tubular damage or a glomerular lesion, urinary NAG activity increases. Elevated NAG levels in urine are an early indication of renal damage, such as injury due to diabetes mellitus, inflammation, nephritic syndrome, urinary tract infection, and more. Various forms of cancer have been associated with increased levels of NAG in serum. Genetically inherited lipid storage disorders, such as Tay-Sachs and Sandhoff disease, arise from deficiencies of the enzyme.

Application: For quantitative determination of ammonia/ammonium concentration by fluorimetry at 360nm/450nm (compatible on handheld fluorimeter catalog# FL360450).

Application: For quantitative determination of aconitase enzyme activity and high-throughput screening assays for aconitase modulator.

Application: Acid Phosphatase activity determination in biological samples (e.g. plasma, serum, cell lysate, tissue samples.).

Application: For quantitative determination of ammonia/ammonium concentration.

Application: For quantitative assay of adipolysis and evaluation of drug effects on adipolysis.

Application: HTS for inhibitor screening and evaluation of acetylcholinesterase inhibitors.

Application; For rapid, quantitative, bioluminescent determination of ATP and evaluation of drug effects on ATP metabolism.

Application: For quantitative determination of ADP determination in cells and other biological samples.