Biocare Medical, LLC products

The process of ion-exchange was first observed by a British chemist in 1850. Ion-exchange is a process, by which one type of ion is absorbed into a solid material and replaced by an equivalent quantity of another ion of the same charge. By using this process, we have formulated an advanced decalcification system that removes calcium from bone quickly while leaving superior cellular detail. The I.E.D. Unit incorporates a strong cation ion-exchange resin in a weak acid solution to remove calcium ions from bone, while replacing them with hydrogen ions. The ion-exchange process does not require strong concentrated acid solutions as in traditional decalcification methods, delicate cellular structures remain intact. This can be very important for immunohistochemistry (IHC) procedures, especially for bone marrow. Over decalcification can destroy morphology that may effect the final staining quality and staining intensity for IHC staining.

Antigen Decloaker is a citrate buffer heat retrieval solution, pH 6.0. Antigen Decloaker can be used with Biocare’s digital electric pressure cooker (Decloaking Chamber), a steamer, a water bath, or a microwave oven. Antigen Decloaker incorporates Assure™ technology, a color-coded high temperature pH indicator solution. The end user is assured by visual inspection that the solution is at the correct dilution and pH. This product is specially formulated for superior pH stability at high temperatures and will help prevent the possibility of losing pH sensitive antigens. Antigen Decloaker is non-toxic, non-flammable, odorless and sodium azide and thimerosal free.