Confocal NL products

The NL5+ is an advanced imaging system designed by Confocal NL for high-speed, high-contrast 3D live cell imaging. This second-generation technology employs a fast line-scanning confocal system that is highly effective for imaging thick specimens, such as tissue samples, organoids, and various model organisms, with high temporal resolution and reduced phototoxicity. The system incorporates a sensitive sCMOS camera and a set of filters that allow for multi-color imaging across six channels. The NL5+ minimizes phototoxic effects while providing improved temporal resolution and an exceptional signal-to-noise ratio, making it suitable for long-duration time-lapse experiments. Running on software like Micromanager and Inscoper, it allows integration into current widefield microscopy setups, transforming them into high-resolution and sensitive confocal systems, meeting the diverse imaging requirements of the research field.

The AION confocal microscopy system by Confocal NL represents the third generation of Line REscan confocal technology designed for high-contrast imaging of live cells and thick specimens. This system excels in long-term, low-signal imaging and features one of the most expansive fields of view available, achieving high sensitivity through camera-based detection combined with visible (VIS) and near-infrared (NIR) imaging capabilities. Its unique design leverages a 25 mm field of view with a motorized pinhole, offering unparalleled confocality and reduced phototoxicity, making it suitable for delicate live cell imaging. The system supports fast imaging with speeds over 1000 frames per second in fixed line mode and operates with wavelengths spanning 400 to 1100 nm. Adding to its versatility, AION can be integrated with existing widefield microscopes, enhancing them with advanced confocal capabilities. The system's robust design, combined with high detector sensitivity and low laser power requirements, makes it an ideal solution for imaging complex biological samples like organoids and zebrafish embryos.

GAIA Point REscan is an advanced super resolution microscope designed to deliver exceptional live cell imaging capabilities. Utilizing patented confocal technology, it enables imaging beyond the diffraction limit with minimal energy consumption. The system is characterized by its low phototoxicity, which is critical for preserving cell viability during extensive imaging sessions. It achieves high resolution by incorporating a synchronized rescanning technique and bespoke optical elements before and after the pinhole to improve field-of-view and resolution. The flagship version, GAIA λ, offers features such as a motorized switchable pinhole for flexibility and sensitivity, and supports a variety of imaging modalities. Its sensitive detector contributes to high quantum efficiency, advantageous for both visible and near-infrared wavelengths. With outstanding adaptability, the GAIA systems offer real-time resolution improvements and support integration with standard commercial microscope bodies, making them ideal for various imaging applications.