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Creative Biolabs services
Conjugate Sites Analysis
As one important aspect in ADC characterization, the identification of the conjugate sites provides an accurate map of the payload positions on a mAb. This set of results is extremely helpful in the prediction/validation of the effects on antigen binding activities induced by the conjugation process and in identification of bio-similarity ADC products. Conjugate sites analysis and determination is achieved by peptide mapping using highly sensitive and accurate LC-MS/MS. https://www.creative-biolabs.com/adc/conjugate-sites-analysis.htmSmall Molecule Inhibitors
Small molecule inhibitors are a class of small molecules that interact with proteins and reduce the biological activity of target proteins. The structure of small molecule inhibitors has good spatial dispersion, and their chemical properties determine their good pharmacodinemic properties and pharmacokinetic properties. These characteristics make small molecule inhibitors show great advantages in drug research and development process, and these molecules are becoming more and more popular in the market.AI-assisted Protein Modeling Services
Generally, the structural information of protein is more valuable than sequence alone for determining its function. Through the three-dimensional (3D) structure of a protein, researchers can understand its biochemical function and interaction properties in molecular detail.AI-assisted Toxicity Prediction Services
Because the use and production of chemical compounds may be directly harmful to humans, animals, plants, or the environment. Chemical toxicity and adverse effects have become key regulatory aspects for a multitude of industries.Cryo-Electron Microscopy
Creative Biolabs can provide custom structure determination services using cryo-electron microscopy for drug discovery.Electron Microscopy
Creative Biolabs can provide custom digital imaging services using electron microscopy with the advanced drug discovery services platform.Fluorescence Microscopy
Creative Biolabs can provide custom digital imaging services using fluorescence microscopy in drug discovery.Confocal Laser Scanning Microscopy
Creative Biolabs can provide custom digital imaging services using confocal laser scanning microscopy with the advanced drug discovery platform.Electron Microscopy
Creative Biolabs can provide custom digital imaging services using electron microscopy with the advanced drug discovery services platform.