Creative Peptides services

Creative-Peptides is a leading supplier of custom peptide APIs, full spectrum of high quality custom peptide synthesis services from high throughput peptide library/array synthesis to high quality bulk API peptides, bioactive catalog peptides and cosmetic peptides. As one of the world`s largest producers of synthetic peptides, Creative-Peptides has developed a variety of proprietary technologies, peptide manufacturing facilities, and expertise that allow us to provide large volume, high quality and complex custom peptides from research grade to GMP production, and giving you the flexibility you need for custom peptides. Creative-Peptides strives to be the most competitive peptide synthesis provider in the world!. Each peptide undergoes mass spectral quality control before shipment; purified peptides are shipped with MS & HPLC analysis data.

Our technical and applications support team can offer advice on library design and experimental set up and analysis. Relating to design, we can advise on the best overlap or offset of peptides to be used in your target application, and then using your full-length protein sequence, we can generate the list of peptides for your library. Assistance with experimental set-up and analysis is available for applications such as ELISPOT, cell culture, intracellular cytokine staining and flow cytometry. The CreativePepTM Peptide Library technology can be used for a number of different types of library: > Overlapping peptide library > Alanine Scanning Library > Truncation Library > Random Library > Positional Scanning Library

Cell penetrating peptides (CPPs), also known as protein transduction domains (PTDs) or membrane transduction peptides (MTPs), are small molecular peptides that consist of 5-30 amino acid residues, which not only penetrate the cell membrane by themselves, but also carry a variety of exogenous substances such as peptides, proteins, nucleic acids and nanoparticles in a covalent or non-covalent binding manner into cells. CPPs have a wide range of transmembrane targets and can enter a variety of cell types, even through the blood-brain barrier when applied in vivo. As an effective bioactive molecular intracellular transport tool, CPPs have broad application prospects in cell biology and cellular immunology, especially in the fields of drug development, gene biotherapy and tumor targeted therapy.

Stable isotope labeled peptides (SIL peptides), also known as heavy peptides, are chemically synthesized peptides with the native sequence, but some of the constituent amino acids are replaced by the stable isotope labeled amino acids, such as 12C by 13C, 14N by 15N, and 1H by 2H. Stable isotope labeled peptides are chemically and physically indistinguishable from their endogenous counterparts with respect to retention time, ionization efficiency and fragmentation mechanism. 

Peptides have inherent properties such as high biological activity, low toxicity, and high specificity. Peptides are now increasingly used in clinical research. A number of peptide drugs are already on the market, and hundreds more are at different stages of clinical development. And GMP peptides can help accelerate the peptide drug development process in the early stages of drug development.

Surface Plasmon Resonance imaging (SPRi), namely surface plasmon resonance microscopy (SPRM), is a real-time, label-free, and high-throughput technique which is used to study biomolecular interactions based on detecting the refractive index changes resulting from molecular binding. More specifically, SPRi has been developed to examine affinity between biomolecules, screen biomarkers and detect biopsy specimens.

Epitope Mapping is an essential aspect in the discovery and development of diagnostic and therapeutic antibodies. It can aid in the selection of optimized therapeutic MAbs, elucidate cancer-specific epitope markers, and define the protective (and in some cases pathogenic) effects of vaccines. Based on our advanced peptide library platform, Creative Peptides provides a comprehensive series of Epitope Mapping Services to fulfill customers` demand. Our Creative Map^TM Platform is developed to map various epitopes flexibly.