CrystalsFirst GmbH products

CrystalsFirst provides crystal-grade proteins from any of the major expression systems, such as bacteria, insect, or mammalian cell lines.Thanks to our state-of-the-art technologies the production process is customized for every need, from mgs to tens of mgs scale. Our quality control ensures the high-quality of the protein material for crystallographic purposes. Methods such as mass spectrometry (MS), analytical size-exclusion chromatography (SEC), circular dichroism (CD), dynamic light scattering (DLS), and thermal shift assay (TSA) are applied routinely to ensure high-quality of protein material for crystallography.

The FastForward is an automated pipeline for processing and smart refinement of crystallographic data. The standardization and automation of the process from raw data to refined structure, enables detection of up to 25% more fragments hits as compared to manual refinement. FastForward as a flexible pipeline can be parallelized for multiple projects delivering a data flow from high throughput crystallographic screenings fast.