Genizer LLC products

Genizer - Model NanoGenizer-|| - Nano High Pressure Homogenizer

NanoGenizer High Pressure Homogenizer: NanoGenizer is a laboratory high pressure processing device. It is an electrically-driven and bench-top, high pressure homogenizer requiring no compressed air or hydraulic oil to achieve maximum 3,062 bar (45,000 psi) operating pressure. NanoGenizer high pressure homogenizer is composed of a feed reservoir, high pressure pump, transducer, PLC control panel and microfluidics diamond interaction chamber. The sanitary pump system of the NanoGenizer high pressure homogenizer is able to supply the desired pressure to the product stream and push it through the micron chamber (microreactor) to create high shear rates and strong impact within the stream. This process results in uniform particle distribution and smaller particle sizes.

Genizer - Model HandGenizer - High Pressure Homogenizer

Portable hand driven homogenizer for concept testing up to 30,000 psi. Low-cost high pressure homogenizer, Portable design delivers the light weight and small dimensions, Convenient hand driven without compressed gas, A better choice for small-scale formulation screening, An alternative to the high pressure homogenizers driven by compressed air

Genizer - Model PilotGenizer - High Pressure Homogenizer

Pilot Scale High Pressure Homogenizer with Dual Pump for continuous pressure up to 45,000 psi.

Genizer - Model GJE - Jacketed Liposome Extruder for Nanosizing liposomes

The Genizer Jacketed Liposome Extruders is compressed air-driven and temperature-controlled, from testing to manufacturing production of liposome and lipopolyplex, for drug and gene delivery. Homogenous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. Genizer Jacketed Liposome Extruders are designed to generate homogeneous unilamellar liposomes and Lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters of defined pore size. The process is relatively gentle, exposing the formulation to moderate pressures up to 3,000 psi at controlled temperatures. The Genizer Jacketed Extruder offers virtually no dead-volume, is easy to clean, suitable for sterilization and in compliance with FDA and GMP sanitary standards in pharmaceuticals.

Diamond Interaction Chamber

Genizer - Model Y-Type - Diamond Interaction Chamber

Y-Type Diamond Interaction Chamber (DIXC) is used to produce uniform nanoparticles in a high pressure homogenizer. The fixed geometry within the Y-Type DIXC is intended to create a uniform processing profile so that all materials will be processed with equal disruptive forces. Single-slotted interaction chambers have a single microchannel and are ideal choices for small batch research, while the multi-slotted interaction chamber comprises multiple microchannels in parallel, which can be used at industrial scales, by increasing the flow rate through the DIXC but with equal processing forces.

Genizer - Model Z-Type - Diamond Interaction Chamber

Z-Type Diamond Interaction Chamber (DIXC) is used to produce uniform nanoparticles in a high-pressure homogenizer. The fixed geometry within the Z-Type DIXC is intended to create a uniform processing profile so that all materials will be processed with equal disruptive forces. Single-slotted interaction chambers have a single microchannel and are ideal choices for small batch research, while the multi-slotted interaction chamber comprises multiple microchannels in parallel, which can be used at industrial scales, by increasing the flow rate through the DIXC but with equal processing forces.

Genizer - Model Assembly - Diamond Interaction Chamber

Diamond Interaction Chamber (DIXC) is used to produce uniform nanoparticles in a high-pressure homogenizer. The fixed geometry within the DIXC is intended to create a uniform processing profile so that all materials will be processed with equal disruptive forces. Single-slotted interaction chambers have a single microchannel and are ideal choices for small batch research, while the multi-slotted interaction chamber comprises multiple microchannels in parallel, which can be used at industrial scales, by increasing the flow rate through the DIXC but with equal processing forces.

Liposome Extruder

Genizer - Liposome HandExtruder

The HandExtruder is a manually powered extruder designed for the formulation of 0.25mL-2.0mL liposome and lipopolyplex with small samples. The sample is passed back through the membrane by being pushed back and forth between two syringes. Homogenous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. The HandExtruder offers minimal dead-volume, is easy to clean and is suitable for sterilization. Temperature control is available.

Genizer - Jacketed Liposome Extruders

Genizer - Online Liposome Extruders

Genizer Online Liposome Extruders can be connected with a sanitary pump or high pressure homogenizer and are temperature controlled, from testing to manufacturing production of pharmaceuical liposomes such as Doxorubicin, Irinotecan and Paclitaxel. Homogenous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. Genizer Online Liposome Extruders are designed to generate homogeneous unilamellar liposomes and lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters of defined pore size. The Online Liposome Extruder offers virtually no dead volume, is easy to clean, suitable for sterilization and in compliance with FDA and GMP sanitary standards in pharmaceuticals.