Invivoscribe, Inc. software

The FLT3 ITD MRD Software is designed for bioinformatic analysis of RAW FASTQ files generated by Illumina MiSeq and other platforms like DNBSEQ-G99 and NextSeq 1000 sequencers. It is specifically used with the FLT3 ITD MRD Assay to identify internal tandem duplications (ITDs) in the FLT3 gene, providing enhanced diagnostic insights into hematolymphoid malignancies. This software generates variant read frequency and confidence data for ITD detection with a particular focus on variant allele frequencies. The output is customizable to integrate into downstream Laboratory Information Management Systems (LIMS) and compatible reporting systems. Data output is provided as .tsv files, allowing for detailed analysis of individual and aggregate sample data. This dockerized Linux-based software is streamlined for flexibility and adaptation, although it is intended solely for research purposes and not for diagnostic use.