LGC BIOSEARCH TECHNOLOGIES products

Whether you require labeled, unlabeled oligos, or PCR primers, LGC Biosearch Technologies can meet your exact needs as we offer custom modifications at extremely competitive rates. Most oligos are shipped in less than five to seven working days. Certificates of Analysis are available upon request.

The MerMade 6/12 Oligonucleotide synthesizer is designed to synthesize DNA, RNA and LNA oligonucleotides in a column format using standard or modified chemistries. The Mermade 6/12 is ideal for a lab requiring medium through put with maximum flexibility.  This instrument has been placed in many universities, pharma and diagnostic companies operating in cGMP environments.  The machine is available in a 6 or 12 column configuration with up to 20 amidite positions. It is capable of making a combination of standard, degenerate, and modified oligos in the same run with scales varying from 50nmole to 200umole (over 400umole with certain supports).  Synthesis time depends on chemistry and desired product quality but a typical run time is less than 2 hours for 12 columns of DNA 20mers. No other machine offers the flexibility, upgrade ability, dependability, efficiency and ease of use than the MM 6 /12 at any cost.

The MerMade 4 Oligonucleotide synthesizer is designed to synthesize DNA, RNA & LNA oligonucleotides in a column format using standard or modified chemistries. The Mermade 4 is designed to replace some of the older designed synthesizers and is capable of making a combination of standard, degenerate, and modified oligos in the same run with scales varying from 50nmole to 5umole.  Synthesis time depends on chemistry and desired product quality but a typical run time is less than 2 hours for 4 columns of 20mers. Priced to compete with other low-through-put machines on the market, the MM 4 is a good choice when looking for an easy to use low cost synthesizer.

The MerMade 8 is designed for customers who want an easy to use flow through column based instrument. Capable of replacing discontinued instruments such as the Expedite and the 390 series Applied Biosystems synthesizers. The MM8 offers modern software and capabilities. Graphical programing allows for easy protocol development of synthesis scales up to 15umole.

The MerMade 96E Oligonucleotide synthesizer is designed to synthesize DNA, RNA & LNA oligonucleotides in a column format using standard or modified chemistries. The 96E can synthesize 96 oligos in less than 2 hours, producing a very high quality product with very minimal reagent usage. This instrument is ideally suited for those who need a fast synthesizer that is still capable of producing high quality oligos with the ability to synthesize oligos with extensive modifications.

The MerMade 192E Oligonucleotide synthesizer is designed to synthesize DNA, RNA & LNA oligonucleotides in a column format using standard or modified chemistries. The 192E can synthesize 192 oligos in less than 3 hours, producing a very high quality product with very minimal reagent usage. The 192E is ideally suited for those who need a fast synthesizer that is capable of producing high quality oligos that do not require extensive modifications.

All that is required to read the fluorescent signal from completed KASP reactions is a FRET-capable plate reader or a qPCR instrument.

Traditional multiplex PCR is inflexible, requiring a “fixed panel” approach to assay development, and limiting its applicability to lab workflows interrogating many samples over a set panel of targets. This unforgiving format can be challenging if you need to analyse several targets in a plant or animal breeding program where targets change from project to project and generation to generation.

Speed is of the essence when it comes to DNA analysis of plant breeding populations. This creates a demand for high-throughput DNA extractions from plant tissues, with resultant purified DNA of a suitable quality for PCR-based applications.

The oKtopure is a robot platform which combines standardises high-throughput DNA extraction from plant tissue with the proprietary sbeadex™ magnetic bead based extraction chemistry.