Nanalysis Corp. applications
There are many useful NMR applications in biotechnology and pharmaceutical industries. 1H and multinuclear NMR Spectroscopy (e.g., 13C, 19F, 31P) are essential tools for structural elucidation and drug discovery. Additionally, they can be used for structural confirmation of both known synthetic drugs and natural products with pharmaceutical effects. See for example, the series of non-steroidal anti-inflammatory drugs (NSAIDs).
Any NMReady-60e or 60PRO can easily be converted into an online detector for in-lab or process line type reaction monitoring via our flow accessory and recommended liquid handling system.
As biodiesel is formed through a simple transesterification, it is easily monitored and characterized by NMR Spectroscopy. This analytical technique allows easy, non-destructive evaluation of many of the components regulated in biodiesel standardization (e.g., water, alcohol, phosphorous, and glycerol content). Subsequently, the NMReady could be easily incorporated into characterization to improve workflow. NMR Spectroscopy can be used to quantify the percentage of biodiesel in composite fuel mixture. Click HERE for a biodiesel spectrum generated on the NMReady and HERE for a related blog entry.
Relaxometry has long been used in food science to determine the solid fat content (SFC), moisture content, etc. Not only can the NMReady perform these fundamental experiments, but, in addition, the option to measure high-resolution 1D 1H NMR acquisition can provide additional invaluable information through speciation (e.g., amount of saturated and unsaturated fats, cis/trans olefin conformations, % carbohydrates). qNMR QA/QC methods are also possible to validate product claims (e.g., carbohydrate content, alcohol percentage, authenticity of the sample or the presence of adulterants).
NMR applications include methods that can be useful in quantifying and speciating dissolved organic matter in earth’s atmosphere, ocean, and soil (e.g., chlorofluorocarbons, benzene, toluene, ethylbenzene & xylene (BTEX), methyl tert-butyl ether (MTBE).