Nautilus Biotechnology products

The Nautilus proteome analysis platform leverages a nanofabricated, large-scale, single-molecule protein array, multi-cycle imaging, and machine learning analysis to potentially identify and quantify the proteome with extreme sensitivity and scale. First, individual, intact protein molecules are immobilized via conjugation to proprietary scaffolds for deposition onto an array with billions of landing pads. Next, multi-cycle imaging allows repetitive, non-destructive probing of individual proteins with unique binding reagents. The results are digitized and analyzed to decode the proteome, potentially enabling quantitative analysis at unprecedented scale over an exceptionally large dynamic range.