On-Line Instrument Systems, Inc. products

The OLIS CPL Solo is designed as a compact and cost-effective solution for circularly polarized luminescence (CPL) measurement. With a focus on high sensitivity and performance, it incorporates advanced optical components such as filtered LED sources for maximum excitation and a high-throughput monochromator paired with a gated photon-counting detector for enhanced emission sensitivity. The system is fully digital, negating the need for a lock-in amplifier or G-factor corrections. It offers two models, one tailored for UV/Vis and the other for NIR, with the capability to measure phosphorescence lifetimes. This makes it versatile for studies involving both polarized and unpolarized excitation. The CPL Solo is noted for its competitive pricing and compact form factor, which does not compromise its technological edge over alternatives like those from Jasco, Applied Photophysics, and Edinburgh Instruments. The product emphasizes modularity, ease of use, and ecological responsibility through upgradeability.

Circular Dichroism and Absorbance in a compact footprint; The smallest CD on the market, the DSM 20 CD is perfectly optimized for the laboratories working on proteins, peptides, and nucleic acids. Exactly like the larger and more ambitious DSM 17 and DSM 1000 CDs, the little 20 uses a dual beam digital acquisition scheme with one permanent calibration value, eliminating all requirements of post-factory calibration. The right answer is the only answer a DSM CD can return.

CLARiTY UV/Vis Spectrophotometers, offered by On-Line Instrument Systems, epitomize advanced spectrophotometric technology designed to measure a wide range of light absorbing samples, from transparent to opaque. Unlike traditional cuvette spectrophotometers that require clear, soluble samples, CLARiTY uses an Integrating Cavity Absorbance Meter (ICAM), allowing the examination of samples in their native forms without preparation to remove turbidity. These spectrophotometers are suitable for various applications including biomolecules, polymers, nanoparticles, and tissue analysis. The systems are configurable for UV, visible, or combined configurations with capabilities to switch between absorbance and fluorescence measurements. Offering rapid scanning, high sensitivity, and modular configurations, CLARiTY instruments can be adapted for specific wavelength needs, ensuring flexibility in both research and practical applications. These features make CLARiTY instruments an essential tool for any laboratory aiming for precision in spectroscopic analysis.

The OLIS CLARiTY 1000 is a cutting-edge integrating cavity spectrophotometer designed for conducting direct spectrophotometric studies under noninvasive physiological conditions. This innovative instrument is adept at examining biological events in their native cellular environment, offering advantages in whole cell studies without disrupting cellular complexity. Unique to its line, the CLARiTY 1000 is capable of rapid-scanning at up to 100 scans per second, significantly enhancing its utility in tracking dynamic processes such as electron transport in mitochondria, the vitamin A cycle in retinal tissues, and cellular fermentation. Unlike traditional spectrophotometers, the CLARiTY 1000 virtually negates the effects of light scatter, maintaining accuracy even in turbid samples. The spectrometer is engineered with a subtractive double monochromator, ensuring zero temporal dispersion and homogeneous output, making it suitable for heterogeneous samples. This instrument sets a new benchmark in performance, ideal for complex biochemical, metabolic, and binding studies.

On-Line Instrument Systems, Inc. offers a robust solution for extending the life and performance of the HP 8453 UV/Vis spectrometer through their upcycling service. With original manufacturers having ceased support, OLIS steps in to provide modernization via their OlisWorks Win 10 software and supportive hardware additions. These enhancements offer comprehensive measurement capabilities in a range from 190 to 1100 nm with 1 nm resolution, accommodating both 2D and 3D data analysis. The upcycling service, besides providing optical performance akin to entirely new systems, ensures sustainability by minimizing waste and maximizing resource usage, supported by high-quality accessories for specific applications like temperature control. With a strong emphasis on ecological and economic responsibility, OLIS offers modular designs that facilitate future upgrades, ensuring longevity and reliability in scientific research environments.