Orochem Technologies Inc. products

Orochem Technologies provides high-performance HILIC chromatography columns and normal phase HPLC columns for the separation of polar and hydrophilic compounds. Hydrophilic interaction chromatography (HILIC) uses a polar stationary phase and aqueous-organic mobile phases to deliver excellent resolution and reproducibility. Normal phase chromatography employs a hydrophilic silica surface with non-polar mobile phases for selective separation based on analyte polarity.

Reverse phase chromatography is the most widely used mode of HPLC, ideal for separating a broad range of compounds from pharmaceuticals to biomolecules. In reversed-phase HPLC, the stationary phase is made of hydrophobic, silane-bonded silica, while the mobile phase is typically a polar solvent such as water mixed with organic modifiers. This setup separates analytes based on hydrophobic interactions, with more non-polar compounds eluting later. Adjusting the mobile phase composition allows fine-tuning for optimal resolution.