PREMIER Biosoft software
Mass Spectrometry
Model SimGlycan - High Throughput Glycan & Glycopeptide Identification Tool using Mass Spectrometry Data
SimGlycan predicts structure of glycans from the MS/MS and multi-stage mass spectrometry (MSn) data. Furthermore, comprehensive support for resolving glycopeptides using LC-MS/MS glycopeptide data facilitates glycosylation studies. SimGlycan accepts experimental MS/MS data, matches them with its own database and finally generate a list of ranked candidate structures. Rank of each candidate indicates the proximity between the candidate structure and the experimental glycan. The rank is calculated based on a robust scoring mechanism that considers structure specific diagnostic ions observed in the experimental MS/MS spectra as well as the intensity of those observed peaks. SimGlycan also supports multistage mass spectrometry (MSn) data analysis for isomers differentiation.
Model SimLipid - High Throughput Lipid Identification and Quantification Software
High throughput lipid characterization tool for data from MSE, TripleTOF, MALDI TOF/TOF, LC-MS, LC-MS/MS systems. SimLipid® is a high throughput lipid identification and quantification software. It can process raw data from hundreds of LC-MS and MS/MS experimental runs for LC-peak detection, peak-picking, molecular feature finding and retention time alignment. The raw data or peaklists – dataset containing processed LC-MS data – can be subjected to MS and MS/MS database search for structural elucidation, even in batch mode. A proprietary scoring mechanism distinguishes isobaric candidate structures for each MS/MS scan.
Genomics
Model AlleleID - Comprehensive Desktop Tool
AlleleID® is a comprehensive desktop tool designed to address the challenges of bacterial identification, pathogen detection or species identification. With ClustalW multiple sequence alignment at its core, AlleleID® can be used to design species identification/cross species probes for microarrays or real time PCR including SYBR® Green, TaqMan® MGB, TaqMan® probes, Molecular Beacons and real time PCR primers. AlleleID® also offers support for designing microarray experiments for detecting alternative splicing events.
Model Beacon Designer - Design Specific and Efficient Oligos for All Major qPCR Assays
Design successful SYBR® Green, TaqMan®, HRMA Primers, MethyLight TaqMan®, LNA™ spiked TaqMan®, molecular beacons for both standard and NASBA® assays, Scorpions® and FRET assays by automatically interpreting BLAST results and avoiding template structures.