RedShift BioAnalytics, Inc. products

Aurora TX by RedShift BioAnalytics is a sophisticated biophysical characterization tool that leverages Microfluidic Modulation Spectroscopy (MMS) technology to provide high-resolution secondary structure information on biomolecules, including RNA, proteins, AAVs, biotherapeutics, and ligand binding events. This benchtop-friendly instrument completely automates the analytical process, from sample analysis to data processing, delivering precise measurements across the Amide I region with one wavenumber spacing. The tool's core, MMS, combines a Quantum Cascade Laser with a microfluidic flow cell and advanced software to perform label-free analysis over a diverse concentration range without needing buffer exchange or dilution. This direct method addresses limitations of traditional spectroscopic analyses, enhancing the ability to monitor biomolecular stability, structure, and aggregation via a simple yet advanced spectral engine. The accompanying delta software transforms this high-quality data into actionable scientific insights, enriching research in protein structure prediction and validation.

The Aurora system by RedShiftBio utilizes Microfluidic Modulation Spectroscopy (MMS) for detailed biomolecular structural analysis. MMS employs a Quantum Cascade Laser alongside a microfluidic flow cell and sophisticated software to deliver high-resolution secondary structure insights into biomolecules like proteins and AAVs. The technique offers precise, ultra-sensitive measurements, tackling traditional spectroscopic challenges by providing direct, label-free analyses across broad concentration ranges within complex buffer formulations, eliminating the need for dilution or buffer exchange. Ideal for applications requiring validation of protein or RNA secondary structure predictions, MMS produces differential absorbance spectra with 1 wavenumber spacing throughout the Amide I region. By evaluating stability, structure, similarity, and aggregation, MMS adds value to analytical processes. The integration with delta software ensures that users can process spectral data with ease, resulting in high-quality, comparative structural output, thus significantly enhancing research outcomes in biophysical characterization and bioprocess analytics.

The HaLCon system by RedShiftBio is a dedicated liquid chromatography device designed for rapid and precise protein titer measurements. Ideal for use within bioprocessing suites, HaLCon offers real-time, HPLC-level data quality, minimizing the need for extensive training or disruption of current workflows. The compact system employs a proprietary trap-and-elute technique to determine IgG concentrations from cell-free samples in under six minutes. It can seamlessly integrate with automated sampling systems, facilitating high throughput operations with reduced wait times for actionable data. HaLCon's design supports a sample capacity of up to 192 (96 well plates) or 96 (2 ml vials) and allows injection volumes of 100 μL, making it a versatile tool for efficient bioprocessing analytics.

The Apollo system by RedShiftBio integrates advanced Microfluidic Modulation Spectroscopy (MMS) technology to offer high-precision structural characterization of biomolecules. Designed for scientists and researchers working with protein therapeutics, Apollo provides ultra-sensitive measurements of molecular structure, enabling deeper insights into stability, integrity, and similarity. Key features include a robust fluidic system and sophisticated detection methods, which combine to deliver a comprehensive view of biomolecular features in a single automation run. The system is accompanied by delta, an intuitive analytical engine that processes data efficiently, generating high-quality, comparative spectral outputs. This flexibility extends to sample analysis as well, allowing use of various well plate geometries for comprehensive quality assessment. By integrating MMS technology, Apollo enhances an analytical suite, delivering assured structural insights critical for the development and quality control of biotherapeutics.