Refined Laser Systems GmbH products

The PICUS DUO from Refined Laser Systems is a sophisticated laser source designed for multicolor Coherent Anti-Stokes Raman Scattering (CARS) and Stimulated Raman Scattering (SRS) imaging applications. It features an all-fiber design that negates the need for water cooling or an isolated table, providing a compact and efficient solution. The system is fully computer-controlled, offering rapid tuning capabilities coupled with a broad tuning range. The OEM variant, tailored for seamless integration, fits into a standard 19-inch enclosure and supports flexible pulse delivery away from the optical table. The built-in electro-optic modulator (EOM) facilitates seamless amplitude modulation of the pump output, enhancing its utility in SRS imaging applications. With noise performance at a relative intensity noise (RIN) of -157 dBc/Hz, the PICUS DUO competes with solid-state Optical Parametric Oscillators (OPOs) while offering added advantages of fiber technology.

The PICUS Q is engineered to meet the rising demands for high brightness and tuning range, optimized particularly for quantum dot pumping. This turnkey fiber laser integrates seamless operation across various technical domains like quantum technology, nanoscience, and semiconductor inspection. It offers rapid wavelength selection with exceptional brightness and coherence, effectively amalgamating the merits of Ti:Sa, supercontinuum, and tunable fiber lasers. Its flexibly tuned wavelength range of 770 to 980 nm, along with customizable spectral bandwidths, ensures precision in optical pumping and spectroscopic analyses. The PICUS Q guarantees ultra-stable performance with minimal power and wavelength deviations over extended durations and high temporal coherence thanks to its resonant optical parametric oscillator. Its automated operation within a compact, fiber-coupled design eliminates the need for water cooling and allows easy integration, making it a reliable choice for research labs worldwide.

The Noctua Stimulated Raman Microscopy System offers innovative imaging solutions that obviate the need for traditional staining processes, enabling the analysis of both fresh and frozen tissue sections. Unlike conventional imaging techniques, Noctua's microscopy system provides label-free, virtual H&E contrast that aligns closely with classic H&E staining. It allows the visualization of cellular structures, such as nuclei and cell bodies, with remarkable clarity. The system excels in exploring physiological structures that are typically inaccessible, showcasing capabilities like identifying unsaturated fatty acids and cholesterol in C. elegans, and revealing lipid-based dermal structures in mouse skin. Equipped with a fiber-coupled balanced detector, the system suppresses laser noise to achieve a superior signal-to-noise ratio, paramount for high-quality imaging. Its rapid tuning capabilities cover a broad spectral range. However, it's crucial to note that its availability is geographically restricted, and interested parties should inquire about its availability in specific regions.