Tosoh India Pvt. Ltd. products

Glycohemoglobin is a general term for the complexes where the whole blood glucose is non-enzymatically bound to α or β-chains of human hemoglobin. Within these complexes, HbA1c, which is the complex of glucose and the N-terminus of the β-chain, is the most prevalent. HbA1c is non-enzymatically synthesized in two steps. In first step labile HbA1c (L-A1c) is formed and in the second step, stable HbA1c (s-A1c) is formed. Due to the fact, L-A1c changes rapidly in response to changes in whole blood glucose concentrations, hence s-A1c is now used to evaluate the diabetes. S-A1c provides the best indication of average glucose levels over the most recent 1 to 3 month period because it does not fluctuate in response to physiological factors. HLC-723G8, an Automated Glycohemoglobin Analyzer based on High Performance Liquid Chromatography (HPLC) designed for quick separation of L-A1c and s-A1c.

Hemoglobin is a tetramer which is composed out of 2 α-chains and 2 non α-chains. In the normal synthesis, α-chains and non α-chains (β-chain, γ-chain and δ-chain) are synthesized with no overproduction or underproduction. Thalassemias are hereditary disorders that are caused by abnormally synthesized globin chains. In thalassemic disorders, due to a quantitative defect in synthesis of a specific chain, free α chains or single globin chains such as HbH(β4), HbBart’s(γ4) of hemoglobin could be synthesized. β-Thalassemia in an analogous manner means reduced or missing production of hemoglobin β-chains, which is compensated by overproduction of γ-chains and δ-chains. Consequently, hemoglobin A2 (α2δ2) and hemoglobin F(α2γ2) are often elevated in β-Thalassemia.

Radiance, a semi-automated chemiluminescence (CLIA) plate analyzer is designed to offer total independence in immunoassay testing and fulfills all the requirements of a small and mid-sized clinical laboratory. With Radiance, it is now possible for any start-up laboratory to initiate routine and esoteric immunoassay testing with high end enhanced pulse CLIA technology. Radiance provides accurate and fast reports which helps in gaining clinician’s confidence.

Tosoh Bioscience`s AIA-2000, a fully automated immunoassay analyzer has become the new global standard for speed and reliability amongst fully featured immunoassay analyzers. Equipped with a complete line of test menu, the user can load up to 960 tests (48 trays x 20 tests) in a new, easy-to-load hybrid sorter; increasing walkaway time to approximately 4 hours. In order to prevent potential carryover disposable tips are used with a loading capacity of 576 tips to increase walkaway time. The AIA-2000 delivers 200 tests / hour including true STAT results in less than 20 minutes per patient, making it an ideal solution for laboratories with high workload. Tosoh Bioscience`s AIA-2000 has been designed to increase workflow and minimize labor time.