Welch Materials Inc. products

Superior quality bare silica and stationary phases synthesized on spherical silica. Rely on Welch’s attention to detail for scalability, reproducibility and high performance. High mechanical strength endures multiple packing/re-packing cycles. Ultra-pure (purity > 99.999% SiO2) silica material with near-zero metals contamination. End-capped materials ensure optimal resolution and peak shape.

Sample preparation is one of the most important steps in any analysis process. SPE has become one of the most powerful preparation techniques for the analytical chromatography of various substances, including urine, blood, water, beverages, soil and animal tissue.

UHPLC users have access to a number of high performance choices, including a selection of Ultisil UHPLC (1.8 micron) phases with overlapping selectivity; Xtimate Hybrid UHPLC phases (C18 and C8); and Welch inline filters and guard columns designed for UHPLC applications.  All Welch UHPLC columns feature

Welch Preparative Columns use the same packing materials as our analytical columns. This ensures predictable scale-up and reproducibility. Packed by prep column specialists, our prep HPLC columns deliver excellent stability of column bed for long life and minimal voiding. The theoretical plate number for 10 μm column is greater than 35000/m; for 5 μm column, it is greater than 75000/m, and the peak symmetry is in the range of 0.95~1.20.

Guard Columns should be deployed in a manner consistent with the column geometry (column diameter), particle geometry (particle diameter), and chemistry (column stationary phase) of the analytical column.

During HPLC analysis, especially when employing gradient elution, some unexpected peaks (usually called “Ghost Peaks”) may appear in the chromatogram.  These unwanted peaks often coelute with analytes of interest.