Xenobiotic Detection Systems International, Inc. services
Licensing and Laboratory Services
Xenobiotic Detection Systems offers a full range of diagnostic services. The XDS-CALUX Assay is ideal for use as a low cost research tool to determine biological activity of a specific substance. It can also be used as a screening assay to measure contamination levels at industrial sites. Once contamination has been determined using the XDS-CALUX assay, the identity of contaminants can be determined using techniques like GC-MS.
BDS CALUX - Screening of Dioxin-Like Compounds (PCDDs, PCDFs, and DL-PCBs)
What is CALUX? The CALUX Assay (Chemically Activated Luciferase Expression) is a screening bioassay for dioxin-like compounds (PCDDs, PCDFs, and DL-PCBs) using a recombinant cell line developed by Dr. Michael Denison, UC Davis, and patented in December 1998.
LUMI-CELL - For Estrogen Receptor - α (ERα)
What is LUMI-CELL? Similar to the CALUX bioassay, LUMI-CELL is a screening assay using a recombinant cell line (Human breast Carcinoma cell “VM7Luc4E2”) containing a stably integrated ER-responsive luciferase reporter gene for detection and relative quantitation of estrogenic or antiestrogenic activity of chemicals or extracts. The LUMI-CELL bioassay was endocrine disruptor compounds developed by Dr. Michael S. Denison, UC Davis.