Clean-Up Anion Exchange Brochure

Rapid Purification Silica PhasesP H A R M A U C TC L E A N - U P ®Reservoirs for Bonded Phase ExtractionsStated Volume (mL) Tube Configuration Bed Diameter (mm) Sorbent Mass (mg)1 Cylindrical 5.5 50-2003 Cylindrical 8.5 50-10006 Cylindrical 12.5 200-200010 Expanded 8.5 50-100015 Cylindrical 15.5 500-200025 Cylindrical 20 500-500075 Cylindrical 27.5 1000-10000150 Cylindrical 38.0 1000-70000Chemistries are offered on these silica sizes... Small Particle (5-20 µm)Intermediate Particle (25-40 µm)Standard Particle (40-60 µm)Large Particle (125-210 µm)Our sorbents can be packed in SPE columns, flash columns and well plates, and are also available in bulk quantities. 1 mL 3 mL 6 mL 10 mL 15 mL 25 mL 75 mL 150 mLC L E A N - U P ®C L E A N - U P ®Solid Phase Sorbent SelectionOrganic Loading & Exchange CapacityIon Exchange - Anion PhasesSorbent Structure pKa % Organic Exchange Applications Loading Capacity (meq/g)Aminopropyl -Si(CH2)3NH2 9.8 6.65 0.310(1° amine)N-2 Aminoethyl -Si(CH2)3NH(CH2)2NH2 10.1, 10.9 9.70 0.320(1° & 2° amine)Diethylamino -Si(CH2)3N(CH2CH3)2 10.6 8.40 0.280(3° amine)Quaternary Amine -Si(CH2)3N+(CH3)3 Cl- Always 8.40 0.250with Chloride Charged counter ion Quaternary Amine -Si(CH2)3N+(CH3)3 CH3CO2- Always 8.40 0.250with Acetate Charged counter ionQuaternary Amine -Si(CH2)3N+CH3)3 OH- Always 8.40 0.250with Hydroxide Charged counter ionQuaternary Amine -Si(CH2)3N+(CH3)3 CHO2- Always 8.40 0.250with Formate Charged counter ionPolyimine -Si(CH2)3-R-[NHCH2CH2]X 13.5 0.85Ion Exchange - Cation PhasesSorbent Structure pKa % Organic Exchange Applications Loading Capacity (meq/g)Carboxylic Acid -SiCH2COOH 4.8 9.10 0.170Propylsulfonic Acid -Si(CH2)3SO3H <1 7.10 0.180Benzenesulfonic Acid -Si-(CH2)2 SO3H Always 11.00 0.320 ChargedBenzenesulfonic Acid -Si-(CH2)2 SO3H Always 15.00 0.650 High Load Charged Triacetic Acid -Si(CH2)3NH-(CH2)2-N(CH2COOH)2 7.61 Anion 0.17 CH2COOH Cation 0.06 Scavenger for acids, cyclic com-pounds, cholesterols, and other lipid type compounds. Scavenger for acids, cyclic com-pounds, cholesterols, and other lipid type compounds. Scavenger for acids, cyclic com-pounds, cholesterols, and other lipid type compounds. Scavenger for acids and sulfonylchlorides, isocyanates andweak electrophiles. Usefulwhen charge on ion beingremoved is stronger than thechloride counter ion.Scavenger for acids and sulfonylchlorides, isocyanates andweak electrophiles. Usefulwhen charge on ion beingremoved is stronger than theacetate counter ion.Scavenger for acids and sulfonylchlorides, isocyanates andweak electrophiles. Usefulwhen charge on ion beingremoved is stronger than thehydroxide counter ion.Scavenger for acids and sulfonylchlorides, isocyanates andweak electrophiles. Usefulwhen charge on ion beingremoved is stronger than theformate counter ion.Scavenger for acids,sulfonyl chlorides,isocyanates andother electrophiles.Scavenger for strongamines with quats.Scavenger for amines,alcohols and othernucleophiles.Scavenger for amines,alcohols and othernucleophiles.Scavenger for amines,alcohols and othernucleophiles.Chelator formetal ions.U C TRemoves larger ormore hydrophobic compounds.Removal of hydrophobic impurities, de-salting and purification of hydrophobic compounds.Removes smallest orleast hydrophobic compounds.Scavenger for phenolic compounds.Scavenger for polar compounds.Solid Phase Sorbent SelectionOrganic Loading & Exchange CapacityHydrophobic PhasesSorbent Structure % Organic Loading ApplicationsC2 ethyl -SiCH2CH3 6.60C3 propyl -Si(CH2)2CH3 7.60C4 n-butyl -Si(CH2)3CH3 8.50Ci4 isobutyl -SiCH2CH(CH3)2 8.80Ct4 tertiary -SiC(CH3)3 8.50C5 pentyl -Si(CH2)4CH3 9.50C6 hexyl -Si(CH2)5CH3 11.00C7 heptyl -Si(CH2)6CH3 11.00C8 octyl -Si(CH2)7CH3 11.10C10 n-decyl -Si(CH2)9CH3 15.70C12 n-dodecyl -Si(CH2)11CH3 15.50C18 octadecyl -Si(CH2)17CH3 21.70C20 eicosyl -Si(CH2)19CH3 24.30C30 tricontyl -Si(CH2)29CH3 26.00Cyclohexyl -Si 11.60Phenyl -Si 11.00Hydrophilic PhasesSorbent Structure % Organic Exchange Applications Loading Capacity (meq/g)Silica -SiOH N/A N/ADiol -Si(CH2)3OCH2-CHOHCH2OH 8.00 N/ACyanopropyl -Si(CH2)3CN 6.90 N/A Removes steroid type compounds.Florisil® N/A N/A Removes polar type compounds.Alumina-Acid N/A N/A Removes polar type compounds.Alumina-Neutral N/A N/A Removes polar type compounds.Alumina-Base N/A N/A Removes polar type compounds.Carbon N/A N/A Removes polar type compounds.Removal of hydrophilic (polar) impurities and purification of hydrophilic (polar) compounds.Removal of hydrophilic (polar) impurities and purification of hydrophilic (polar) compounds.C L E A N - U P ®Solid Phase Sorbent SelectionOrganic Loading & Exchange CapacityCopolymeric (Multifunctional Phases)Sorbent Structure % Organic Exchange Applications Loading Capacity (meq/g)Aminopropyl -Si(CH2)3NH2 & -Si(CH2)7CH3 12.3 0.163+ C8Quaternary Amine -Si(CH2)3N+(CH3)3 & -Si(CH2)7CH3 13.60 0.160+ C8Carboxylic Acid -SiCH2COOH & -Si(CH2)7CH3 12.50 0.105+ C8Propylsulfonic Acid -Si(CH2)3SO3H & -Si(CH2)7CH3 14.62 0.114+ C8Benzenesulfonic -Si-(CH2)2 SO3H & -Si-(CH2)7CH3 12.30 0.072Acid + C8Cyanopropyl -Si(CH2)3CN & -Si(CH2)7CH3 14.60 0.163+ C8Cyclohexyl -Si & -Si-(CH2)7CH3 N/A N/A+ C8Covalent PhasesSorbent Structure % Organic Exchange Applications Loading Capacity (meq/g)Epoxy -Si-(CH2)3- O - CH2- CH - CH2 N/A N/A OAldehyde -Si(CH2)4CHO N/A N/AIsocyanate -Si(CH2)3NCO 7.1 N/AThiopropyl -Si(CH2)3SH 6.50 N/ACovalent bond formation with proteins,amines and other nucleophiles.Scavenger for primary amines, hydrazines,reducing agents and other nucleophiles. Covalent bonding for proteins, enzymes and other bioactive molecules.Scavenger for amines, alkoxides and other nucleophiles.Scavenger for alkylating agents,alcohols and amines.Dual functionality for strong acids and hydrophobic compoundsDual functionality for weak acids and hydrophobic compoundsDual functionality for strong bases and hydrophobic compoundsDual functionality for weak bases and hydrophobic compoundsDual functionality for weak bases and hydrophobic compoundsDual functionality for polar and hydrophobic compoundsDual functionality for phenols and hydrophobic compoundsP H A R M APRICES AND TERMSOur prices are subject to change without notice. The price in effect when we receive your order will apply. All prices are in US Dollars and are F.O.B. Lewistown, PA 17044. Terms of payment are net 30 days. MINIMUM ORDERSWe welcome all orders, therefore, we do not have a mini-mum order requirement. When ordering, please include your purchase order number, complete “Ship To” and “Bill To” address, catalog number, quantity, and descrip-tion of product(s). Also include your name and a phone number where you can be reached should we have any questions concerning your order. SHIPMENTSNormal processing is within 24 hours after receipt of an order. Unless special shipping requests have been made, our trained staff will send all orders by UPS Ground ser-vice. The appropriate shipping charges (freight & insur-ance costs) will be added to the invoice, unless otherwise instructed by the customer.SPECIAL PRICINGWe offer special pricing for volume purchases and standing orders. These discounts apply to bonded phase extraction column purchases only. Please call a sales representative for more information on special pricing qualifications.RETURN POLICYOur Quality Manager will handle all returns. Before return-ing merchandise, please call to obtain a return authorization number from the quality manager. We will need to know the reason for the return, date of purchase, purchase order number and invoice number in order to issue a return authorization number. Return merchandise must be received before a credit can be issued. Returns will not be accepted after 90 days. A restocking fee of 25% of the price paid, or a minimum of $25.00 (whichever is greater) will be charged on all returns. WARRANTYAll products manufactured by UCT are guaranteed against defects in materials and workmanship for a period of 90 days after shipment. UCT will replace any items that prove to be defective during this time period. The exclusive remedy requires the end user to first ad-vise UCT of the defective product by phone or in writing. Secondly, the defective product must be returned within 30 days after proper approval from our Quality Manager. All returns must indicate the purchase order number, the lot number and the shipping date. UCT’s total liability is limited to the replacement cost of UCT products. This warranty does not apply to damage resulting from misuse.Placing An OrderPhone: 215.781.9255 800.541.0559Fax: 215.785.1226MailUCT, LLC 2731 Bartram Rd. Bristol, PA 19007Technical SupportPhone: 215.781.9255 800.385.3153Fax: 215.785.1226Email: info@unitedchem.comForum: forums.unitedchem.comWeb: www.unitedchem.comC L E A N - U P ®U C TDCN-116270-02