Hygieia - Escherichia Coli Bacterin - Brochure

The cell walls of gram negative bacteria (such as E. coli, Salmonella, Pasteurella. etc.) contain endotoxin as an integral structural element. Due to the similarity between these structural endotoxin elements (the so-called "core antigens"! across many families of gram negative bacteria, immunity against one has been shown to confer some immunity against the others. This is the basis for the development of core antigen vaccines such as J-5.