Introduction to DNA Methylation

DNA methylation, one of the most studied epigenetic modifications, refers to the addition of a methyl group to the fifth carbon of cytosine (C) catalyzed by DNA methyltransferases (Dnmts), forming 5-methylcytosine (5mC). DNA methylation predominantly occurs in CpGs but is also found in non-CpG contexts. https://www.cd-genomics.com/Epigenomics.html