LEAP - Mini Purific without Pumps and UV Detector - Brochure

Unique DesignTwo heads “one injects and one collects” for low carry-over• Reliable two syringe concept for higher throughput• Syringe only concept eliminates errors from Tefl on tubing or transfer lines• Flexibility for sample tray and collection tubes• Pumps and versatile UV detector• Driven by PEAK Harvester™ software with graphical real-time tracking• Precise sample handling for dependable purifi cation results• Anti-static solvent lines• Automated switching procedures to clean and equilibrate columns• Double the throughput with optional 10 port valvewww.leaptec.com - info@leaptec.com - 800-229-8814 - PO Box 969 Carrboro, NC 27510 - www.leapwiki.com Purifi c Two Fraction Injectors/CollectorsThe Purifi c is the latest fully automated turn-key system from LEAP for isolating target compounds from complex samples. It is compatible with a wide range of sample sizes and a wide range of HPLC columns.Applications• Purifi cation for biological or sensory evaluation (e.g. DMPKA)• Replace older fraction collectors• Pilot plant production• Flash chromatographyLB Purifi c (Large Bed) L: 1428mm D: 1000mm H: 670mm Huge Capacity Fraction CapacitySemi-Prep1296 2ml vials24 deepwell plates (96 or 384 wells)1092 Test Tubes 13x100mm (9ml)700 Test Tubes 16x100mm (12ml)700 Test Tubes 16x150mm (20ml) 504 Test Tubes 18x150mm (27ml) 504 Test Tubes 20x150mm (34ml) 294 Test Tubes 25x150mm (55ml) 12 Gilson 215 RacksMini Purifi c L: 690mm D: 690mm H: 690mm Small Footprint Fits Fume Hood Fraction CapacitySemi-Prep6 deepwell plates (96 or 384 wells) 234 Test Tubes 13x100mm (9ml) 150 Test Tubes 16x100mm (12ml) 150 Test Tubes 16x150mm (20ml) 108 Test Tubes 18x150mm (27ml) 108 Test Tubes 20x150mm (34ml) 63 Test Tubes 25x150mm (55ml) 2 Gilson 215 Racks (Large Bed) L: 1428mm D: 1000mm H: 670mm 24 deepwell plates (96 or 384 wells)1092 Test Tubes 13x100mm (9ml)700 Test Tubes 16x100mm (12ml)700 Test Tubes 16x150mm (20ml) 504 Test Tubes 18x150mm (27ml) 504 Test Tubes 20x150mm (34ml) 294 Test Tubes 25x150mm (55ml)OPTIONS• Regular and cooled stacks for 2ml vials (6x 54 pos per stack); 3 stacks• Regular and cooled stacks for 18 deepwell plates• Additional valve drive with 10-port valve for higher throughput• Customized tube racksTHE ACTIVE WASH STATIONYour system should detect everything...except carryover• Two, self priming, PTFE micro pumps capable of aspiration from below the lab bench • Two wash solvent reservoirs (e.g. organic and aqueous) • Cleaning solvent fl ows through the valve groove inside the needle seal and is also aspirated to wash the syringe THE SOLVENT DELIVERY MODULE (Pumps)• Wide range of fl ow rates, virtually all application needs are covered• Smooth, precise solvent fl ow and system pressure are maintained with a built-in pressure unit • User friendly pump heads are self-contained units that can be rapidly exchanged by simply loosening a fi nger-tight clamp• Piston wash option dramatically extends seal life in biochromatography applications using high concentration salt buffers • Flow accuracy: ±1% of selected fl ow rate or ±0.05% of maximum fl ow rate, whichever is larger (0.1% for 5 mL heads)• Flow reproducibility: ±0.1% of selected fl ow rate or ±0.05% of maximum fl ow rate, whichever is larger (0.1% for 5 ml heads)THE UV Vis DETECTORThe Dual Wavelength UV-Vis Detector from LEAP delivers superb sensitivity and a wide dynamic absorbance range• The extended absorbance range of the dual path length fl ow cells dramatically reduces the need for sample dilutions - saving valuable time• Supports detection up to 40 absorbance units higher than most UV Vis detectors• Deuterium source provides stable, precise wavelength settings in the ultraviolet spectrum and Quartz halogen lamp covers the visible range • Simultaneously handles two user defi ned wavelengths• Interchangeable cartridge-style fl ow cells handle microliter per minute fl ow rates to hundreds of mililiters per minute• Routine maintenance is easy with front panel access. Thumb screws secure the lamps and fl ow cells making access and exchange “tool-free”THE DUAL PROBE DESIGNInjection syringe• Standard PAL injection setup with 19 gauge needle and semi-prep LC valveCollection syringe concept with only 4 microliter dead volume • Provides true high throughput processing never achieved before by conventional auto purifi cation solutions• Commonly used 3 way diverter valve is replaced by a unique side-port syringe that guarantees an extremely low dead volume between valve and collection outlet• Special diverter valve design reduces the risk of fraction carryover• Use of septa or non-septa vials PEAK Harvester™ Software Control • Specifi cally designed to control every single step of the purifi cation process• Allows control of the LC pumps and detector•“Smart” fraction collection on two signals simultaneously: time and/or slope and/or threshold• Vial selection dynamic or static allowing pooled fractions• Color coded sample and fraction tracking lets you review and report an enormous amount of analytical data • Open access interface lets you walk up and log in your samples anytime• Accepts sample list in different formats like CSV or XML • Bar code capable• Choice of collection pattern• Inject and collect from any racks or stacks• Save solvent and stop run after collection• Signal noise cancelling system• UV Wavelength part of the sample methodTIME-BASED Using individual time slices per samplePEAK-BASED Using an analog signal or reading data directly from a detectorMASS-BASED Option Using an output signal of the MS for Mass fractionationSPE Option Prepare, Filter, Dilute, Concentrate, Solvent Switchwww.leaptec.com - info@leaptec.com - 800-229-8814 - PO Box 969 Carrboro, NC 27510 - www.leapwiki.com