MiniVap - - Microplate Evaporator Brochure

M I C R O P L A T E E V A P O R A T O R SMicroplate evaporatorsPorvair evaporators are designed to removethe traditional laboratory ‘bottleneck’ ofsolvent evaporation from microplates prior toanalysis or reconstitution in storage buffer.These evaporators give significant throughputadvantages to laboratories looking to optimisemicroplate sample preparation productivity.Faster than centrifugal evaporation,significant increases in sample throughput areachieved through advanced evaporator headtechnology and an innovative manifolddesign, which directly injects heated nitrogeninto each individual well of the microplatesimultaneously. The evaporators have beendesigned to be simple to install, operate andmaintain. Installation requires only connectionto a gas supply or cylinder and mainselectricity. Safety of operation is ensured asthe CE marked compact units fit into all fumecupboards. Not suitable for high boilingsolvents such as DMSO and water.Both MiniVap and UltraVap may be operatedwith a supply of clean, dry compressed air inplace of nitrogen, if the chemistry allows. Anin-line gas filter must be used in this case.MiniVap™The MiniVap is purpose designed for low usageresearch and development departments wherelow numbers of individual plates or vials needdrying. The MiniVap is simple to operate andmaintain. Installation requires only connection to agas supply and standard mains socket. With manualcontrol of the needle depth, gas temperature andflow rate, it allows fine control and quicker dryingtimes than other standard methods.? Quicker dry down times than standard methods such as vacuum oven? Tests have shown that the MiniVap can evaporate 500µl of methanol in less than 6 minutes? Designed for any ANSI/SBS 96 well plate? 24 vial head now available? Simple to install and operate? Easy adjustments of temperature, gas flow rates and needle depth into the wells? Compact footprint – fits all standard fume cupboardsE Q U I P M E N T – M I C R O P L A T E E V A P O R A T O R SCUSTOM MANUFACTURELIFE SCIENCESSTORAGE/COLLECTIONAUTOMATION ACCESSORIESSOLID PHASE EXTRACTIONTISSUE CULTURE & EPIGENETICSW W W . M I C R O P L A T E S . C O MMiniVap 229201MiniVap 229205E Q U I P M E N T – M I C R O P L A T E E V A P O R A T O R SMiniVap™ blowdown sample concentratorMiniVapE Q U I P M E N T – M I C R O P L A T E E V A P O R A T O R SW W W . M I C R O P L A T E S . C O MCUSTOM MANUFACTUREAUTOMATION ACCESSORIESLIFE SCIENCESSTORAGE/COLLECTIONSOLID PHASE EXTRACTIONTISSUE CULTURE & EPIGENETICSNitrogen blow-downThe nitrogen blow-down principle is easy tounderstand. Warm gas is blown down intothe wells of the microplate, just above theliquid level. The effect is to speed up solventevaporation by providing more energy for thelatent heat of evaporation. This enables asteady-state equilibrium to be reached morequickly, leading to shorter drying times.Nitrogen blow-down has been shown to bethe easiest way to automate the frequentbottlenecks caused by the requirement toremove solvent from samples that need to beconcentrated, dried or reconstituted in a moresuitable solvent.Flexible programmingThe Ultravap RC has been designed to allowrobots with extended gripper arms to placeand remove microplates directly onto theevaporation table. In comparison withprevious models, the Ultravap RC is22mm shorter at the front end, allowingbetter access for the gripper arms. Theevaporation table is able to rise under thecontrol of a stepper motor as the dryingprocess proceeds. This can be programmed ata suitable rate for each solvent type beingevaporated. In addition, gas temperature,pressure and flow rate can all be programmedindividually and stored in one of ninemultistep programmes on the UltravapRC. Each programme allows the tableto rise in two distinct ramped phases,so that a fast initial drying period canbe followed by a gentler final dryingphase.With the addition of the optionalclear acrylic side sheets and the 4inch fume duct adaptor, the newUltravap RC unit lends itself to fullintegration with Tecan and Hamilton roboticliquid handlers, where it is usually located onthe right-hand side of the deck. Controlcommands are sent directly from the robotcontroller to the Ultravap. These standardcommands are listed in the manual, but mostrobot manufacturers have drivers available tocontrol the Ultravap, making integration aseamless process.Solvent compatibilityWith a choice of 96 straight or 96 spiral needles, plus 24 and384 straight needles, the sphere of application for UltravapRC is huge. Most common chromatography solvents can beevaporated with ease, such as dichloromethane, methanol,acetonitrile and hexane. The nitrogen blow-down method isnot, however, suitable for high-boiling point solvents such asDMF, DMSO and water. It is also unable to be used with acidsor acid chlorides, as special corrosion-resistant systems areneeded for this work. The choice of straight or spiral needlesallows the user to choose between faster dry down (spiral)and better final drying in V-well plates (straight). The spiralscause a vortex to form in the solvent, increasing the surfacearea and thus speeding up the rate of evaporation. However,for plates with V-bottom wells, or for smaller wells such asthose in 384-well plates, straight needles are required.Evaporator System RequirementsGas flow rate: 28L/min minimum, 80L/min maximum at 6 bar pressure.Can be used with nitrogen or dry compressed air if thechemistry allows.Not suitable for use with strong acids or acid chlorides.UltraVap RC 229135P/N 420001 © Porvair Sciences Limited 2012.Produced by Cream Ink Limited www.creamink.comPrinted in the UK.Customer ServicesPorvair Sciences LtdClywedog Road SouthWrexham Industrial EstateWrexham North WalesUK LL13 9XSTel: +44 (0) 1978 666240/666239Fax: +44 (0) 1978 660007AccountsPorvair plc7 Regis PlaceBergen Way Kings LynnNorfolk UK PE30 2JWTel: 44 (0)1553 765500Fax: +44 (0)1553 765599Sales OfficePorvair Sciences LtdDorset House Regent ParkKingston Road LeatherheadUK KT22 7PLTel: +44 (0)1372 824290Fax: +44 (0)1372 824271email: int.sales@porvair-sciences.comwww.microplates.com