Model STA-383 - Serum Protein Assays and Reagents - Manual

Human serum albumin (HSA) is the most abundant protein in human blood plasma. Albumin constitutes about half of the blood serum protein. It is soluble and monomeric. The typical albumin concentration in blood is around 5 g/dL (50 mg/mL). It is produced in the liver as preproalbumin, which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. Albumin transports hormones, fatty acids, and other compounds, buffers pH, and maintains osmotic pressure.