Tobacco Services Brochure

800-1 Capitola DriveDurham, NC 27713-4385ADDRESS SERVICE REQUESTEDwww.enthalpy.comtobacco@enthalpy.com919.850.4392LeadershipSelected ArticlesRainey, P.; Gillman, G.; Shi, X.; Cheng, T.; Stinson, A.; Gietl, D.; Albino, A.P. “Fluorescent Detection of Lipid Peroxidation Derived Protein Adducts upon In-Vitro Cigarette Smoke Exposure.” Toxicology Mechanisms and Methods, 2009, 19, 401-409Albino, A.P.; Jorgenesen, E.D.; Rainey, P.; Gillman. G.; Clark, T.J.; Gietl, D.; Zhao, H.; Traganos, F.; Darzynkiewicz, Z “?H2AX: A Potential DNA Damage Response Biomarker for Assessing Toxicological Risk of Tobacco Products.” Mutation Research, 2009, 678, 43–52.Wagner, K.A., Finkel, N.H., Fossett, J.E., Gillman I.G., “Development of a Rapid and Quantitative Method for the Analysis of Tobacco Specific Nitrosamines in Mainstream Cigarette Smoke Using Isotope Dilution Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry” Analytical Chemistry, 2005, 77, 1001-1006.Find out what you’ve been missing.Communication. Speed. Service.Learn why Enthalpy has been known as the premiere provider for sample analysis and customer service for 18 years to the emissions testing industry.Tel: 919.850.4392 Fax: 919.850.9012Web: www.enthalpy.comE-mail: tobacco@enthalpy.comEnthalpy Analytical, Inc. 800-1 Capitola DriveDurham, NC 27713-4385Lab Director BiographyGene Gillman is Enthalpy’s Laboratory Director. Dr. Gillman has considerable experience investigating the constituents and chemistry of tobacco smoke, and in developing and validating relevant LC, LC-MS, GC-MS and biological based test methods.He brings experience from both the cigarette manufacturing and a tobacco testing CRO perspectives. In his most recent position, he was the laboratory manager of an ISO 17025 accredited laboratory specializing in qualitative and quantitative analysis of tobacco smoke. Dr. Gillman works with domestic and international study groups and trade organizations.Education: Ph.D. Chemistry, Wake Forest University B.S. Chemistry, Appalachian State University Full-Service Laboratory for Smoke & Tobacco AnalysisIMPORTANT FDA UPDATE:March 2012 – FDA’s draft guidance has been issued requiring testing for an abbreviated list of Harmful and Potentially Harmful Constituents (HPHCs) in Cigarette Smoke, Tobacco and Cigarette Filler as well as Smokeless Tobacco. Contact Enthalpy Analytical to schedule your testing today, in order to meet your December 22, 2012 deadline. Founded in 1993, Enthalpy has been at the forefront of emission measurements for almost 20 years. Whether your project is routine or requires extensive R&D, Enthalpy is your single-source solution.Guided by the founding principles of providing accurate, timely, and cost-effective analytical solutions, Enthalpy is the name to trust in this heavily-regulated environment. History AccreditationsInstrumentationStaff• 4 Ph.D. Scientists • 15 Analysts and Technicians • 4 Project Managers • 4 QA Specialists • National Environmental Laboratory Accreditation Conference (NELAC) Accredited in NJ, LA, TX, VA• Accredited to the ISO17025 standard by the American Association for Laboratory Accreditation (A2LA)• Not all testing referenced is A2LA accredited; consult scope #3198.01 for specific information.www.enthalpy.com919.850.4392 tobacco@enthalpy.comEnthalpy specializes in the analysis of chemical constituents found in cigarette smoke including volatile and semi-volatile organic compounds, nitrosamines, polyaromatic hydrocarbons, aromatic amines, phenols, carbonyls and aldehydes, CO, nicotine and tar.Services OfferedRegardless of scope, every project is assigned one of four project managers to ensure project goals and client expectations are exceeded.Project ManagementCommunication. Speed. Service.>> Enthalpy receives, analyzes & reports over 1,700 projects annually.Hoffmann ListFDA ComplianceOur list of target analytes includes compounds from the”Hoffmann List” as well as the list of HPHCs recently released by the FDA. Among Enthalpy’s instruments is a state-of-the-art Rotary Smoke Machine.>> Single point of contact offered to all customers.>> Our newly-expanded facility is now accepting your smoke and tobacco samplesTest Lab Cert 3198.01• 2 Triple Quad GC/MS/MS• 4 gas-phase FTIR spectrometers • 5 GCs configured with MS detectors• 16 GCs configured with FID, FPD, TCD, PID detectors• 11 HPLCs and ICs configured with UV and EC detectors