YMC - Aqueous Buffers System - Brochure

Downstream processing of monoclonal antibodies and other recombinant proteins requires large volumes of buffer to maintain pH and conductivity during chromatographic purification steps and to stabilize proteins during hold steps and processing. YMC’s Buffer In-line Dilution (BID) systems with digitally controlled, diaphragm metering pumps and optimized fluidic design deliver a precise and accurate flow of both buffer concentrate and diluent. This ensures better control of final buffer composition and minimizes the variation of critical quality attributes, such as (ionic strength, concentration, pH, and conductivity).