Profacgen Offers Protein-Fluorophore Bioconjugation to Fit Research Needs

Profacgen, a state-of-the-art protein service provider that proving custom protein services in the biological field, now proudly provides customer-focused solutions, equipped with the latest technologies of protein-fluorophore bioconjugation, to fit its customers’ special interests.

 The use of fluorescence-based detection of single biomolecules under physiological conditions opens new doors for studying biological problems. Fluorophore bioconjugation technology has become a major tool in biological science because of its ability to achieve target visualization and rapid detection of proteins. Most often, amine reactive fluorophores (e.g., NHS esters) are used to react with free amines present on the N-terminus or lysine side chain of the protein of interest, thereby creating stable covalent bonds. Recent developments in bioconjugation chemistry have made it possible to target amino acid sides other than lysine.

Site-specific labeling of proteins takes advantage of the reactivity of different amino acid side chains, resulting in the selective incorporation of one or more fluorophores. Perfect methods as well as other methods being developed will greatly advance our understanding of key biological mechanisms.

 With many years of experience in protein chemistry, Profacgen offers a variety of fluorophore bioconjugation protocols:

 Conventional amine based fluorescent labeling using NHS esters;

Thiol-reactive fluorophores for cysteine labeling;

Tyrosine-fluorophore bioconjugation;

Clickable fluorophores for azide-containing proteins;

Other customized labeling services.

 “We have a large selection of fluorescent reagents with different spectral properties, interdisciplinary research team with well-experienced technicians. And we provide full support from ideas, through process trouble-shooting, to delivery.” Commented Crystal, the chief marketing staff at Profacgen.

Moreover, Profacgen has developed a series of protein labeling techniques and reagents to meet different research needs and to ensure the quality of downstream applications. And services can be tailored according to specific needs.

 For more information regarding Profacgen’s protein-fluorophore bioconjugation service, please visit https://www.profacgen.com/protein-fluorophore-bioconjugation.htm.