TOPTITECH - 10-20 microns Stainless Steel Sintered Powder Filter for Liquid Chromatography

TOPTITECH stainless steel sintered powder filter is an advanced filtration element specifically engineered for liquid chromatography systems. Manufactured using 316L stainless steel through high‑temperature vacuum sintering, it features a uniform three‑dimensional porous structure that provides stable flow, high mechanical strength, and exceptional chemical compatibility. This design enables precise particle retention and consistent fluid distribution, making it suitable for protecting chromatographic columns, pumps, and detectors from particulate contamination. Its rigid all‑metal construction ensures excellent pressure and temperature resistance, supporting long‑term operation under demanding analytical and industrial conditions.  

With filtration accuracy options ranging from 0.5 μm to 20 μm, the stainless steel sintered filter effectively removes fine impurities and protects sensitive components without introducing extractables or contamination. It is compatible with common chromatographic solvents such as methanol, acetonitrile, and water, while maintaining mechanical integrity during backwashing or ultrasonic cleaning. The filter’s high durability and reusability significantly reduce maintenance frequency and operating costs, offering a reliable solution for HPLC, UHPLC, and preparative chromatography systems where purity and stability are critical.

Material: 316L

Diameter: 11.7mm

Length: 19.9mm

Pore size: 10-20 microns

Technique: Sintered

1. True 3D Isotropic Pore Structure for Uniform Flow Distribution‌

Sintered powder filters are formed by high-temperature diffusion and bonding of millions of metal particles, creating a ‌3D isotropic pore network‌. This structure ensures uniform fluid pressure and velocity distribution, preventing channeling phenomena and significantly improving solvent baseline stability, reducing pressure fluctuations, and enhancing retention time repeatability and peak shape symmetry in HPLC systems.

2. Excellent Chemical Inertness and Pressure Resistance‌

The filter exhibits excellent chemical inertness and pressure resistance, remaining stable under various liquid chromatography modes even when using corrosive mobile phases, without releasing pollutants that could interfere with sample detection.

3. Simultaneous Interception of Microbubbles and Microparticles, Improving Baseline Noise

Liquid chromatography systems are sensitive to both bubbles and particles, which can cause pressure fluctuations and baseline drift. The isotropic pore structure of sintered powder has a "dual effect" of slowing down bubble release and homogenizing flow rate. When the solvent contains a small amount of soluble gas, the micropores of the sintered powder promote the slight dissolution of bubbles and buffer their entry into the chromatographic flow path, thereby significantly reducing baseline noise.

4. Superior Regeneration Performance for Repeated Use‌

The filter has superior regeneration performance; its filtration performance can be fully restored after ultrasonic cleaning or high-temperature sterilization, making it suitable for repeated use in laboratory-scale liquid chromatography analysis, whereas ordinary stainless steel filters show significantly decreased performance after regeneration.

1. Pre-Column and In-Column Filtration  

   Installed upstream of chromatographic columns to remove micro-particulates, protecting the stationary phase from clogging and extending column lifespan.

2. Mobile Phase Filtration and Degassing Systems

   Used in solvent lines to eliminate particulates and gas bubbles, ensuring stable flow and pressure for precise analytical results.

3. Sample Preparation and Analytical Protection  

   Applied in sample introduction systems to prevent needle or injector blockage in HPLC and LC-MS setups, maintaining reproducibility in trace analysis.

4. Preparative Chromatography and Industrial Separation Units  

   Ideal for large-scale purification of biochemical or pharmaceutical compounds, where durability and high flow capacity are essential.

5. Instrument and Pump Protection

   Serves as a safeguard for high-pressure pumps, mixing chambers, and detectors, minimizing downtime and maintenance caused by contamination.

6. Solvent Recovery and Recycle Systems

   Effective in closed-loop chromatographic systems or solvent reclamation units to remove suspended solids before reuse.