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MedChemExpressModel DSPE-PEG-Amine, MW 2000 ammonium -474922-26-4

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DSPE-PEG-Amine, MW 2000 (ammonium), an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents[1][2][3].
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DSPE-PEG-Amine, MW 2000 ammonium

MCE China:DSPE-PEG-Amine, MW 2000 ammonium

Brand:MedChemExpress (MCE)

Cat. No.HY-125924

CAS:474922-26-4

Synonyms:DSPE-PEG-NH2, MW 2000 ammonium; DSPE-PEG(2000) Amine ammonium

Purity:99.96%

Storage:-20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Shipping:Room temperature in continental US; may vary elsewhere.

Description:DSPE-PEG-Amine, MW 2000 (ammonium), an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.

In Vitro:DSPE-PEG-Amine (MW 2000) (ammonium) is coated on the surface of the fluorescein diacetate (FDA) nanocrystals to provide a interface for the antibody coupling. The DSPE-PEG-Amine (MW 2000) (ammonium)-modified biolabels have a highly stable colloidal suspension with minimized nonspecific interactions. The adsorbed DSPE-PEG-Amine (MW 2000) (ammonium) layer causes the FDA nanocrystals to disperse in water and prevents their aggregation, hence conferring colloidal stability[3].

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References:

[1]. Feilong Sun, et al. A Mixed Micelle Formulation for Oral Delivery of Vitamin K. Pharm Res. 2016 Sep;33(9):2168-79.  [Content Brief]

[2]. Brian R Sloat, et al. In Vitro and in Vivo Anti-Tumor Activities of a Gemcitabine Derivative Carried by Nanoparticles. Int J Pharm. 2011 May 16;409(1-2):278-88.  [Content Brief]

[3]. Cangel Pui-yee Chan, et al. Nanocrystal Biolabels With Releasable Fluorophores for Immunoassays. Anal Chem. 2004 Jul 1;76(13):3638-45.  [Content Brief]

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