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MedChemExpressModel Sulfaquinoxaline -59-40-5

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Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections[1][2].
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Sulfaquinoxaline

MCE China:Sulfaquinoxaline

Brand:MedChemExpress (MCE)

Cat. No.HY-B1282

CAS:59-40-5

Purity:98.0%

Storage:Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Shipping:Room temperature in continental US; may vary elsewhere.

Description:Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections.

In Vivo:Sulfaquinoxaline shows the presence of all antimicrobial residues at concentration higher than the drugs' maximum residue limit (MRL) of 100 μg/kg until two days after discontinuation of the medication[2].

Animal Administration:For the depletion studies, 240 1-day-old Cobb chicks are used. The chickens are housed in pens that contains 30 birds each (10 birds/m2) and are provided ad libitum access to water and non-medicated feed. The chickens are randomly allocated into four experimental groups, labeled from A to D, containing 80 birds each. Chickens in group A form the untreated control group, whereas those in groups B, C and D are treated with 10 mg/kg bw of enrofloxacin, Sulfaquinoxaline or oxytetracycline, respectively, which is administered via drinking water from the 32nd to 34th day of breeding[1].

IC50 & Target:Coccidia

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References:

[1]. de Assis DC, et al. Evaluation of the Presence and Levels of Enrofloxacin, Ciprofloxacin, Sulfaquinoxaline and Oxytetracycline in Broiler Chickens after Drug Administration. PLoS One. 2016 Nov 15;11(11):e0166402.  [Content Brief]

[2]. Urbano VR, et al. Influence of pH and ozone dose on sulfaquinoxaline ozonation. J Environ Manage. 2017 Jun 15;195(Pt 2):224-231.  [Content Brief]

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