Bioporto - Model ABS 004-22 -Anti-Complement Component C9 (Human) Mouse Monoclonal Antibody

Specificity:ABS 004-22 is specific for complement factor C9.

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Cat. No. ABS 004-22
Immunogen Complement factor C9
Host Mouse
Positive Species Reactivity Human
Negative Species Reactivity Not determined
Isotype IgG1/k
Gene ID 735
Clone Number 22
Epitope Specificity Not determined
Unit Size 400 µL: Cat. No. ABS 004-22-04 1 mL: Cat. No. ABS 004-22-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification Protein-A/G purified, from culture supernatant
Form Liquid
Solvent 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation Unconjugated BSA free
Storage 4-8ºC without exposure to light. No precautions necessary during handling.
Target Complement factor C9 is a 71kDa single-chain ellipsoid a-globular molecule of 558 amino acids including a leader sequence of 20 amino acids. C9 bind the C5b8 complex on membranes and has an unique property in forming tubular structures containing between 12 and 18 monomers, closely resembling the membrane attack complex (MAC). The primary site of synthesis is hepatocytes, secondary sites are monocytes, fibroblasts and glial cells. The normal level of C9 in plasma is 60 µg/mL, and the level is up regulated from hepatocytes by IFN-g.

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