AMT - Bioreactors for Biotech Membranes

Surface Chemistry

AMT has tailored membrane surface chemistries available for compatibility with differing cell lines. We can make membrane surfaces containing amides, imides, hydroxyl groups and amino groups. Silicone, fluoro-polymer, cellulosic and polypropylene surfaces are also available.

Pore Size Control

AMT can produce tightly controlled pore sizes and distribution using its proprietary coating technology. This is particularly advantageous for culturing valuable immunoglobulins whose size range is over 100KD. AMT’s fibers are design-engineered for cell culture. Pore sizes available include 50KD, 100KD, and 500KD ultra-pores and .01and .2 micron microporous fibers.

Fiber Physical Stability

AMT’s composite fibers are stronger than commonly used dialysis-type fibers. Their pore sizes are essentially locked into place via our manufacturing technique, thus allowing higher feed pressures and operating temperatures without breakage or pore size leakage of valuable bio-components.

Membrane Chemical Stability/Purity

AMT’s bioreactor fibers and modules contain zero extractables and are made from FDA grade materials. The membranes are solvent resistant, as well as resistant to most sterilizing agents.

AMT’s bioreactors represent the most advanced membrane materials for cellular growth and increased production of biologically “active” cell products.