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Pharmigene, Inc.
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  5. Pharmigene - Model HLA-B*1502 - ...

Pharmigene - Model HLA-B*1502 -Carbamazepine & Phenytoin RT-PCR & SYBR Green Based Detection Kit

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RT-PCR & SYBR Green based detection method: each sample requires only 2 PCR rxns for detecting of Human Leukocyte Antigen (HLA-B*1502) and Internal Control. Analysis is based on Ct values. A complete kit version has IVD approval from Department of Health, Taiwan.

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PCR detection
DNA test
DNA testing
DNA sequencing
genotyping
DNA sample
  • Required only hours from blood sample to results.
  • Designed for easy operation & analysis.
  • Validated accuracy with 4500+ patients samples* & DNA sequencing.
  • Protected by US, Europe & world wide patents.
  • Mix & Match design.

Regulatory Status
HLA-B*1502 Detection

  • Taiwan IVD
  • China IVD
  • US ASR

Many studies have demonstrated the strong association of Human Leukocyte Antigen (HLA-B*1502) and carbamazepine, phenytoin, & oxcarbazepine induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Individuals that use DNA tests to determine their HLA genotypes prior to taking these drugs can reduce their risks of developing SJS/TEN by as high as 1300 times.