Brookhaven - Model BI-MwA -Chromatography Detector

Two ways to use the BI-MwA

Determine the molecular weight distribution (flow mode) or determine the average molecular weight (batch mode). Macromolecular samples often have a range of molecular weights. In some cases, this distribution is quite narrow, and in other cases, it is very broad and/or multimodal. Variations in the distribution can indicate the presence of impurities or aggregation. However, for other applications, the average molecular weight is sufficient to characterize your sample. Sometimes the distribution is of interest, and sometimes the overall average is sufficient. Either way, the BI-MwA is the right tool for the job.

Simple to use, sophisticated features

Inject your sample into the low-volume, 7-angle flow cell. The sample is illuminated by a temperature-stabilized, precision power-controlled diode laser. The ultra-stable, high-sensitivity, low-noise CCD detector automatically collects the scattered light. Then, the software extrapolates the data to zero angle for the absolute molecular weight determination.

• Multiangle, laser light scattering detector for SEC/GPC or stand-alone use
• Proteins & polymers
• Polysaccharides & biopolymers
• Study protein aggregation, oligomerization, & complex formation
• M_n, M_w, M_z, R_g, A₂
• Small footprint, stackable
• RI and Viscosity detectors optional

Cell/Optics

• Angles: 7, nominally 35, 50, 75, 90, 105, 130, and 145 degrees.
• Fiber: Low numerical aperture, integral to cell.
• Maximum Pressure: 3.5 MPa (500 psi) maximum.
• Fittings: Standard HPLC Inlet/Outlet on the front panel.
• Volume: Cell, 100 µL nominal; Scattering, 20 nL nominal.
• Laser: Temp. stabilized w/prec. power control, 30 mW, 635 nm, vertically polarized.
• Cell: PEEK std., options on request.

Electronics/Detector

• Control: Integrated, dedicated, powerful microcontroller. USB driven.
• Detector: CCD, ultra-high sensitivity, and spatial uniformity.
• Analog Inputs: 4 standard, with 16 and 24-bit resolution, and 15 additional analog channels (optional) with 24-bit resolution. Computer selectable gain adjustment. Suitable for use with most common RI, UV, viscometer, thermocouple, thermistor, injector, pressure gauge, and pump outputs.
• Power Requirements: 100/115/220/240 VAC, 50/60 Hz,25 Watts
• Dimensions: Size: 195(H) x 210(W) x 380(D) mm; Weight: 5.5 kg
• Certificates: CE Certified