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Rock Imager 1®Crystal Clear Imaging in a Compact Unit

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Rock Imager 1 (RI1) is an automated imaging system for protein crystallization that supports virtually every microplate format. This easy-to-use solution captures superior-quality images in a compact, benchtop unit.
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Application:

  • Protein crystallization imaging in pharmaceutical, biotechnology, and academic laboratories
  • High-throughput crystal screening and monitoring
  • UV fluorescence imaging for distinguishing protein crystals from salt crystals
  • Optimized imaging for LCP, sitting drop, hanging drop, and microbatch crystallization methods


Benefits:

Systems You Can Trust:
Used worldwide by the top 25 pharmaceutical companies and renowned academic centers.

Image Quality Second to None:
Every imaging technology is precisely optimized for crystal-clear images.

Increase Your Throughput:
Image entire 96-well plates in only 3 minutes.

 

Key Features:

  • Intelligent imaging and superior optics provide industry-leading image quality
  • Visible and UV fluorescence imaging
  • Single plate capacity
  • Compatible with SBS, Linbro, Nextal, and LCP plate types
  • Seamless integration with Rock Maker or current crystallization software via Rock Imager API
  • Proprietary drop location algorithm
  • Multi-capture capabilities
  • Extended Focus Imaging (EFI)
  • Auto focus and exposure
  • Region of Interest (ROI)
  • Low-vibration robotics
  • Barcode scanner with on-the-fly scanning

Technical Data: 

Camera:
7.1 MP monochrome CMOS camera; captures high-quality images at up to 51 frames per second.

Optics:
Visible-UV hybrid optics available with a three-objective compound zoom and optical resolution up to 1 μm.
Optical Zoom options:

  • 2x
  • 3.3x
  • 6.6x

Lighting:
A Köhler light source with motorized condenser provides high-contrast images with no sample heating and reliable drop location.

  • Motorized top and bottom polarizers.
  • Optional dark field and glancing illumination.

Performance:
Image entire 96-well plates in only 3 minutes with coarse sectioning and fixed exposures.
Routine imaging of 400 nL drops with auto exposure and EFI in ~5 minutes (visible) and ~10 minutes (UV).
For the best possible images, automatic drop location, autofocus, and visible imaging take ~15 minutes per plate.

Drop Location:
Proprietary automated lighting and image recognition reliably locate drops, including LCP.

Extended Focus Imaging (EFI):
Combines multiple slices into one image for increased contrast and sharpness while maintaining depth.

Region of Interest (ROI):
Automatically captures a specified region of a drop in high resolution.

Compatibility:
SBS, Linbro, Nextal, and thin glass LCP plates; supports hanging drop, sitting drop, microbatch, and LCP setups.

Environmental Requirements:
Operating temperature: 4–30°C
Humidity: 0–80%

Electrical Requirements:
Rock Imager 1: 110–240 V, 50–60 Hz, 144 W
Computer: 575 W
Total Watt Requirement: 719 W

Dimensions (H × W × D):
556 × 419 × 361 mm
Weight: 23 kg