Cytonome/ST, LLC
Cytonome Hydris - Industrial-Scale Cell Purification System
FromCytonome/ST, LLC
Introducing the Hydris high throughput cell purification system. Using the power of parallel technology and advanced automation to improve the efficiency of routine and repetitive cell sorting tasks.
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Building on the proven design and worldwide operational experience of the Cytonome Genesis III™ platform, the Cytonome Hydris™ system leverages the power of full-scale, high-throughput cell sorting by means of parallel architecture with optimized droplet sorting technology. The Cytonome Hydris™ system can leverage custom, application-specific designs with independent sort head monitoring for ease-of-use. The innovative design provides increased efficiency and productivity benefits and thus can contribute significantly to lean manufacturing.
- Up to three (3) sort head assemblies running in parallel
- Individually dedicated sort head performance monitoring
- Jet-in-air droplet sorting reliability
- Optical and laser upgrade paths
- Optional biohazard containment module(s)
- Automated control systems
- High throughput combined sort speeds
- Sorting efficiency and reliability
- Proven performance, reliability
- Flexibility in sorting applications
- Safety for lab personnel
- Walk-away sorting
Cell Types
- Mammalian
- Additional cell types possible (i.e. yeast, bacteria)
Sample Concentration
- 1,000 to 100 million cells per ml (cell type dependent)
Sample Flow Rate
- 4 ml per hour (three 12 x 75mm tubes as input)
Cell Measurement Parameters
- Light scatter, Phycoerythrin (PE) emission (standard)
- Additional fluorescence wavelengths possible
Cell Analysis Rate
- Up to 1 billion cells per hour
Cell Purification Rate
- Up to 300 million cells per hour (depending upon your application)
Sort Collection Vessels
- 1.5 ml, 5 ml, 15 ml, 50 ml tubes; cell culture flasks
- Other collection devices possible
Sort Purity
- >99%
Biohazard Containment
- Optional biological safety cabinet and aerosol evacuation systems
Sort Technology
- Microdroplet sorting
Flow Cell Type
- Ceramic tip, 70 micron orifice (standard)
- Optional disposable polymer tips
Laser Wavelength
- 488 nm (blue) (standard)
- Additional laser wavelengths available
Optical Detection
- Photomultipliers
Sensitivity
- < 250 molecules of equivalent fluorescein
Signal Dynamic Range
- 1 to 50,000 (4.5 orders of magnitude)
Connectivity
- Ethernet
- Additional remote display monitor (HDMI, touch)
User Alerts
- Sort status, run errors
Dimensions
- 122 cm x 89 cm x 204 cm (48 in x 35 in x 80 in)
Facility Requirements
- Single 110/240V AC outlet, compressed gas, vacuum