NEST - Desktop Semi-Automatic Filling and Stoppering Machine
The NEST desktop semi-automatic filling and stoppering machine is an integrated device that combines both filling and stoppering functions. Designed for laboratory use, it is compatible with a variety of packaging formats made from different materials—such as prefilled syringes, cartridges, and vials composed of COC, COP, and others. The system ensures aseptic operation by utilizing a high-precision peristaltic pump for filling and a vacuum-based stoppering mechanism.
Introduction
Key Features and Configuration
Control System
a) Touchscreen interface supporting both Chinese and English
b) Filling control system capable of storing multiple sets of filling data for easy record-keeping and review
c) Integrated control cabinet within the unit for a more compact footprint
Filling Module
a) Utilizes a high-precision stainless steel peristaltic pump, customizable via parameter settings to meet different filling needs
b) Filling volume: 0.5mL - 20mL, with accuracy controlled within ±2%
c) Throughput: approximately 300 vials per hour
d) Servo-motor-driven needle holder enables programmable filling curves tailored to different drug types and volumes. During filling, the needle is inserted into the vial and moves with the liquid level, effectively preventing air bubbles and splashing.
Stoppering Module
a) Features vacuum stoppering, suitable for prefilled syringes and cartridges. Each unit undergoes vacuum level detection during the stoppering process. Adjustable vacuum settings help control bubble formation, significantly improving stoppering success rates.
b) Vacuum stoppering minimizes rubber stopper deformation and helps preserve surface coatings on the stoppers.
