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MedChemExpressModel Phillygenin -487-39-8

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Phillygenin (Phillygenol) is an active ingredient from Forsythia with many medicinal properties, such as antioxidant, reducing blood lipid, inhibition of low density lipoprotein oxidation.
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Phillygenin

MCE China:Phillygenin

Brand:MedChemExpress (MCE)

Cat. No.HY-N0483

CAS:487-39-8

Synonyms:Phillygenol; Epipinoresinol methyl ether; (+)-Phillygenin

Purity:98.97%

Storage:4°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Shipping:Room temperature in continental US; may vary elsewhere.

Description:Phillygenin (Phillygenol) is an active ingredient from Forsythia with many medicinal properties, such as antioxidant, reducing blood lipid, inhibition of low density lipoprotein oxidation.

In Vitro:1) Phillygenin shows a greater inhibition on mouse B16 melanoma cells potential than vincristine[1]. 2) phillygenin had notable scavenging activity against DPPH, ABTS radicals, as well as potent reducing power in FRAP assay.

In Vivo:The reference for rat is 5.6 mg/m l ( i.v).

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References:

[1]. Ye LH et al. Determination of phillygenin in rat plasma by high-performance liquid chromatography and its application to pharmacokinetic studies. Eur J Drug Metab Pharmacokinet, 2013 Sep, 38(3):201-7.  [Content Brief]

[2]. Song W et al. Interaction between phillygenin and human serum albumin based on spectroscopic and molecular docking. Spectrochim Acta A Mol Biomol Spectrosc, 2012 Jan, 85(1):120-6.  [Content Brief]

Brand introduction:
•   MCE (MedChemExpress) has a global exclusive compound library of more than 200 kinds, and we are committed to providing the most comprehensive range of high-quality small molecule active compounds for scientific research customers around the world;
•   More than 50,000 highly selective inhibitors and agonists are involved in various popular signaling pathways and disease areas;
•   The products cover a variety of recombinant proteins, peptides, commonly used kits, more PROTAC, ADC and other characteristic products, widely used in new drug research and development, life science and other scientific research projects;
•   Provide virtual screening, ion channel screening, metabolomics analysis detection analysis, drug screening and other professional technical services;
•   It has a professional experimental center and strict quality control and verification system;
•   Provide LC/MS, NMR, HPLC, chiral analysis, elemental analysis and other quality inspection reports to ensure the high purity and high quality of products;
•   The biological activity of the products has been verified by the experiments of customers in various countries;
•   A variety of top journals such as Nature, Cell, Science and pharmaceutical patents have included the scientific research results of MCE customers;
•   Our professional team tracks the latest pharmaceutical and life science research and provides you with the latest active compounds in the world;
•   It has established long-term cooperation with the world's major pharmaceutical companies and well-known scientific research institutions。