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EtonBio - Model PAK2KD -Recombinant Human PAK2 Kinase Domain
PAK2KD is a recombinant wild type human PAK2 kinase domain (amino acids 227–524 of full-length human PAK2) expressed in E. coli and purified to near homogeneity with high specific activity.PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
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- The calculated mass is 33,510. PAK2KD is fully phosphorylated at T402 and partially phosphorylated at additional sites with measured mass of 33,593 (1P), 33,673 (2P), 33,753 (3P), and 33,834 (4P).
- Stability and Storage:
- Stable at -70oC for 12 months from date of receipt. Protein should be thawed on ice. Protein can be flash-frozen in liquid nitrogen and stored at -70oC.
- Applications:
- Enzymatic studies, inhibitor screen, and selectivity profiling
- High concentration available for crystallization